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Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMR
To accomplish key physiological processes ranging from drug metabolism to steroidogenesis, human microsomal cytochrome P450 enzymes require the sequential input of two electrons delivered by the FMN domain of NADPH-cytochrome P450 reductase. Although some human microsomal P450 enzymes can instead ac...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4759177/ https://ncbi.nlm.nih.gov/pubmed/26719338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677294 |
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