Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease

Por Repanas, Kostas, Zingler, Nora, Layer, Liliana E., Schumann, Gerald G., Perrakis, Anastassis, Weichenrieder, Oliver
Publicado em 2007

The impact of transposable element activity on therapeutically relevant human stem cells

Por Schumann, Gerald G., Fuchs, Nina V., Tristán-Ramos, Pablo, Sebe, Attila, Ivics, Zoltán, Heras, Sara R.
Publicado no Mob DNA (2019)

The Flow of the Gibbon LAVA Element Is Facilitated by the LINE-1 Retrotransposition Machinery

Por Meyer, Thomas J., Held, Ulrike, Nevonen, Kimberly A., Klawitter, Sabine, Pirzer, Thomas, Carbone, Lucia, Schumann, Gerald G.
Publicado no Genome Biol Evol (2016)

Retrotransposons in the development and progression of amyotrophic lateral sclerosis

Por Savage, Abigail L, Schumann, Gerald G, Breen, Gerome, Bubb, Vivien J, Al-Chalabi, Ammar, Quinn, John P
Publicado no J Neurol Neurosurg Psychiatry (2019)

Evolutionary Histories of Transposable Elements in the Genome of the Largest Living Marsupial Carnivore, the Tasmanian Devil

Por Gallus, Susanne, Hallström, Björn M, Kumar, Vikas, Dodt, William G, Janke, Axel, Schumann, Gerald G, Nilsson, Maria A
Publicado no Mol Biol Evol (2015)

APOBEC3B Activity Is Prevalent in Urothelial Carcinoma Cells and Only Slightly Affected by LINE-1 Expression

Por Jaguva Vasudevan, Ananda Ayyappan, Kreimer, Ulrike, Schulz, Wolfgang A., Krikoni, Aikaterini, Schumann, Gerald G., Häussinger, Dieter, Münk, Carsten, Goering, Wolfgang
Publicado no Front Microbiol (2018)

5′-Transducing SVA retrotransposon groups spread efficiently throughout the human genome

Por Damert, Annette, Raiz, Julija, Horn, Axel V., Löwer, Johannes, Wang, Hui, Xing, Jinchuan, Batzer, Mark A., Löwer, Roswitha, Schumann, Gerald G.
Publicado em 2009

Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation

Por De Luca, Chiara, Guadagni, Fiorella, Sinibaldi-Vallebona, Paola, Sentinelli, Steno, Gallucci, Michele, Hoffmann, Andreas, Schumann, Gerald G., Spadafora, Corrado, Sciamanna, Ilaria
Publicado no Oncotarget (2015)

The non-autonomous retrotransposon SVA is trans-mobilized by the human LINE-1 protein machinery

Por Raiz, Julija, Damert, Annette, Chira, Sergiu, Held, Ulrike, Klawitter, Sabine, Hamdorf, Matthias, Löwer, Johannes, Strätling, Wolf H., Löwer, Roswitha, Schumann, Gerald G.
Publicado em 2012

Analysis of 5′ junctions of human LINE-1 and Alu retrotransposons suggests an alternative model for 5′-end attachment requiring microhomology-mediated end-joining

Por Zingler, Nora, Willhoeft, Ute, Brose, Hans-Peter, Schoder, Volker, Jahns, Thomas, Hanschmann, Kay-Martin O., Morrish, Tammy A., Löwer, Johannes, Schumann, Gerald G.
Publicado em 2005

Functional endogenous LINE-1 retrotransposons are expressed and mobilized in rat chloroleukemia cells

Por Kirilyuk, Alexander, Tolstonog, Genrich V., Damert, Annette, Held, Ulrike, Hahn, Silvia, Löwer, Roswitha, Buschmann, Christian, Horn, Axel V., Traub, Peter, Schumann, Gerald G.
Publicado em 2008

Endogenous LINE-1 reverse transcriptase activity in platelets controls translational events through RNA-DNA hybrids

Por Schwertz, Hansjörg, Rowley, Jesse W., Schumann, Gerald G., Thorack, Ulrike, Campbell, Robert A., Manne, Bhanu Kanth, Zimmerman, Guy A., Weyrich, Andrew S., Rondina, Matthew T.
Publicado no Arterioscler Thromb Vasc Biol (2018)

2098: Endogenous reverse transcriptase (LINE-1) in human platelets regulates cell morphology and protein synthetic events

Por Schwertz, Hansjorg, Rowley, Jesse W., Kraiss, Larry W., Moran, John V., Campbell, Robert A., Zimmerman, Guy A., Weyrich, Andrew S., Thomas Rondina, Matthew, Schumann, Gerald G., Thorack, Ulrike
Publicado no J Clin Transl Sci (2018)

Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis

Por Savage, Abigail L., Lopez, Ana Illera, Iacoangeli, Alfredo, Bubb, Vivien J., Smith, Bradley, Troakes, Claire, Alahmady, Nada, Koks, Sulev, Schumann, Gerald G., Al-Chalabi, Ammar, Quinn, John P.
Publicado no Mol Brain (2020)

APOBEC4 Enhances the Replication of HIV-1

Por Marino, Daniela, Perković, Mario, Hain, Anika, Jaguva Vasudevan, Ananda A., Hofmann, Henning, Hanschmann, Kay-Martin, Mühlebach, Michael D., Schumann, Gerald G., König, Renate, Cichutek, Klaus, Häussinger, Dieter, Münk, Carsten
Publicado no PLoS One (2016)

Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity

Por Horn, Axel V., Klawitter, Sabine, Held, Ulrike, Berger, André, Jaguva Vasudevan, Ananda Ayyappan, Bock, Anja, Hofmann, Henning, Hanschmann, Kay-Martin O., Trösemeier, Jan-Hendrik, Flory, Egbert, Jabulowsky, Robert A., Han, Jeffrey S., Löwer, Johannes, Löwer, Roswitha, Münk, Carsten, Schumann, Gerald G.
Publicado em 2014

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

Por Klawitter, Sabine, Fuchs, Nina V., Upton, Kyle R., Muñoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Cañadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Merkert, Sylvia, Gerdes, Patricia, Pulgarin, J. Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Sarkadi, Balázs, Löwer, Johannes, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltán, Izsvák, Zsuzsanna, Garcia-Perez, Jose L., Faulkner, Geoffrey J., Schumann, Gerald G.
Publicado no Nat Commun (2016)

Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

Por Klawitter, Sabine, Fuchs, Nina V., Upton, Kyle R., Muñoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Cañadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Merkert, Sylvia, Gerdes, Patricia, Pulgarin, J. Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Sarkadi, Balázs, Löwer, Johannes, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltán, Izsvák, Zsuzsanna, Garcia-Perez, Jose L., Faulkner, Geoffrey J., Schumann, Gerald G.
Publicado no Nat Commun (2018)

Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration

Por Fukuda, Shinichi, Varshney, Akhil, Fowler, Benjamin J., Wang, Shao-bin, Narendran, Siddharth, Ambati, Kameshwari, Yasuma, Tetsuhiro, Magagnoli, Joseph, Leung, Hannah, Hirahara, Shuichiro, Nagasaka, Yosuke, Yasuma, Reo, Apicella, Ivana, Pereira, Felipe, Makin, Ryan D., Magner, Eamonn, Liu, Xinan, Sun, Jian, Wang, Mo, Baker, Kirstie, Marion, Kenneth M., Huang, Xiwen, Baghdasaryan, Elmira, Ambati, Meenakshi, Ambati, Vidya L., Pandey, Akshat, Pandya, Lekha, Cummings, Tammy, Banerjee, Daipayan, Huang, Peirong, Yerramothu, Praveen, Tolstonog, Genrich V., Held, Ulrike, Erwin, Jennifer A., Paquola, Apua C. M., Herdy, Joseph R., Ogura, Yuichiro, Terasaki, Hiroko, Oshika, Tetsuro, Darwish, Shaban, Singh, Ramendra K., Mozaffari, Saghar, Bhattarai, Deepak, Kim, Kyung Bo, Hardin, James W., Bennett, Charles L., Hinton, David R., Hanson, Timothy E., Röver, Christian, Parang, Keykavous, Kerur, Nagaraj, Liu, Jinze, Werner, Brian C., Sutton, S. Scott, Sadda, Srinivas R., Schumann, Gerald G., Gelfand, Bradley D., Gage, Fred H., Ambati, Jayakrishna
Publicado no Proc Natl Acad Sci U S A (2021)

Gibbon genome and the fast karyotype evolution of small apes

Por Carbone, Lucia, Alan Harris, R., Gnerre, Sante, Veeramah, Krishna R., Lorente-Galdos, Belen, Huddleston, John, Meyer, Thomas J., Herrero, Javier, Roos, Christian, Aken, Bronwen, Anaclerio, Fabio, Archidiacono, Nicoletta, Baker, Carl, Barrell, Daniel, Batzer, Mark A., Beal, Kathryn, Blancher, Antoine, Bohrson, Craig L., Brameier, Markus, Campbell, Michael S., Capozzi, Oronzo, Casola, Claudio, Chiatante, Giorgia, Cree, Andrew, Damert, Annette, de Jong, Pieter J., Dumas, Laura, Fernandez-Callejo, Marcos, Flicek, Paul, Fuchs, Nina V., Gut, Ivo, Gut, Marta, Hahn, Matthew W., Hernandez-Rodriguez, Jessica, Hillier, LaDeana W., Hubley, Robert, Ianc, Bianca, Izsvák, Zsuzsanna, Jablonski, Nina G., Johnstone, Laurel M., Karimpour-Fard, Anis, Konkel, Miriam K., Kostka, Dennis, Lazar, Nathan H., Lee, Sandra L., Lewis, Lora R., Liu, Yue, Locke, Devin P., Mallick, Swapan, Mendez, Fernando L., Muffato, Matthieu, Nazareth, Lynne V., Nevonen, Kimberly A., O’Bleness, Majesta, Ochis, Cornelia, Odom, Duncan T., Pollard, Katherine S., Quilez, Javier, Reich, David, Rocchi, Mariano, Schumann, Gerald G., Searle, Stephen, Sikela, James M., Skollar, Gabriella, Smit, Arian, Sonmez, Kemal, Hallers, Boudewijn ten, Terhune, Elizabeth, Thomas, Gregg W. C., Ullmer, Brygg, Ventura, Mario, Walker, Jerilyn A., Wall, Jeffrey D., Walter, Lutz, Ward, Michelle C., Wheelan, Sarah J., Whelan, Christopher W., White, Simon, Wilhelm, Larry J., Woerner, August E., Yandell, Mark, Zhu, Baoli, Hammer, Michael F., Marques-Bonet, Tomas, Eichler, Evan E., Fulton, Lucinda, Fronick, Catrina, Muzny, Donna M., Warren, Wesley C., Worley, Kim C., Rogers, Jeffrey, Wilson, Richard K., Gibbs, Richard A.
Publicado no Nature (2014)