2098: Endogenous reverse transcriptase (LINE-1) in human platelets regulates cell morphology and protein synthetic events

OBJECTIVES/SPECIFIC AIMS: Endogenous RT (eRT) is necessary for the function of retrotransposons, elements that replicate via an RNA intermediate. One source of eRT activity is long interspersed elements (LINE). LINEs, of which there are several subgroups (L1, L2, L3), are retrotransposons that regul...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: Schwertz, Hansjorg, Rowley, Jesse W., Kraiss, Larry W., Moran, John V., Campbell, Robert A., Zimmerman, Guy A., Weyrich, Andrew S., Thomas Rondina, Matthew, Schumann, Gerald G., Thorack, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2018
Assuntos:
Mechanistic Basic to Clinical
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799451/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.202
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