2098: Endogenous reverse transcriptase (LINE-1) in human platelets regulates cell morphology and protein synthetic events

OBJECTIVES/SPECIFIC AIMS: Endogenous RT (eRT) is necessary for the function of retrotransposons, elements that replicate via an RNA intermediate. One source of eRT activity is long interspersed elements (LINE). LINEs, of which there are several subgroups (L1, L2, L3), are retrotransposons that regul...

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Vydáno v:J Clin Transl Sci
Hlavní autoři: Schwertz, Hansjorg, Rowley, Jesse W., Kraiss, Larry W., Moran, John V., Campbell, Robert A., Zimmerman, Guy A., Weyrich, Andrew S., Thomas Rondina, Matthew, Schumann, Gerald G., Thorack, Ulrike
Médium: Artigo
Jazyk:Inglês
Vydáno: Cambridge University Press 2018
Témata:
Mechanistic Basic to Clinical
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799451/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.202
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