2098: Endogenous reverse transcriptase (LINE-1) in human platelets regulates cell morphology and protein synthetic events

OBJECTIVES/SPECIFIC AIMS: Endogenous RT (eRT) is necessary for the function of retrotransposons, elements that replicate via an RNA intermediate. One source of eRT activity is long interspersed elements (LINE). LINEs, of which there are several subgroups (L1, L2, L3), are retrotransposons that regul...

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Detaylı Bibliyografya
Yayımlandı:J Clin Transl Sci
Asıl Yazarlar: Schwertz, Hansjorg, Rowley, Jesse W., Kraiss, Larry W., Moran, John V., Campbell, Robert A., Zimmerman, Guy A., Weyrich, Andrew S., Thomas Rondina, Matthew, Schumann, Gerald G., Thorack, Ulrike
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cambridge University Press 2018
Konular:
Mechanistic Basic to Clinical
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799451/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.202
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