2098: Endogenous reverse transcriptase (LINE-1) in human platelets regulates cell morphology and protein synthetic events

OBJECTIVES/SPECIFIC AIMS: Endogenous RT (eRT) is necessary for the function of retrotransposons, elements that replicate via an RNA intermediate. One source of eRT activity is long interspersed elements (LINE). LINEs, of which there are several subgroups (L1, L2, L3), are retrotransposons that regul...

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Bibliografische gegevens
Gepubliceerd in:J Clin Transl Sci
Hoofdauteurs: Schwertz, Hansjorg, Rowley, Jesse W., Kraiss, Larry W., Moran, John V., Campbell, Robert A., Zimmerman, Guy A., Weyrich, Andrew S., Thomas Rondina, Matthew, Schumann, Gerald G., Thorack, Ulrike
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cambridge University Press 2018
Onderwerpen:
Mechanistic Basic to Clinical
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799451/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.202
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