Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation

LINE-1 (L1) retrotransposons are a source of endogenous reverse transcriptase (RT) activity, which is expressed as part of the L1-encoded ORF2 protein (L1-ORF2p). L1 elements are highly expressed in many cancer types, while being silenced in most differentiated somatic tissues. We previously found t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: De Luca, Chiara, Guadagni, Fiorella, Sinibaldi-Vallebona, Paola, Sentinelli, Steno, Gallucci, Michele, Hoffmann, Andreas, Schumann, Gerald G., Spadafora, Corrado, Sciamanna, Ilaria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826189/
https://ncbi.nlm.nih.gov/pubmed/26716650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6767
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