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Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease
The human LINE-1 endonuclease (L1-EN) is the targeting endonuclease encoded by the human LINE-1 (L1) retrotransposon. L1-EN guides the genomic integration of new L1 and Alu elements that presently account for ∼28% of the human genome. L1-EN bears considerable technological interest, because its targ...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950540/ https://ncbi.nlm.nih.gov/pubmed/17626046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm516 |
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