Decomposing the Energetic Impact of Drug-Resistant Mutations: The Example of HIV-1 Protease - DRV Binding

od Cai, Yufeng, Schiffer, Celia
Izdano u Methods Mol Biol (2012)

Resilience to Resistance of HIV-1 Protease Inhibitors: Profile of Darunavir

od Lefebvre, Eric, Schiffer, Celia A.
Izdano 2008

Decomposing the energetic impact of drug resistant mutations in HIV-1 protease on binding DRV

od Cai, Yufeng, Schiffer, Celia A
Izdano 2010

REdiii: a pipeline for automated structure solution

od Bohn, Markus-Frederik, Schiffer, Celia A.
Izdano u Acta Crystallogr D Biol Crystallogr (2015)

APOBEC3s: DNA‐editing human cytidine deaminases

od Silvas, Tania V., Schiffer, Celia A.
Izdano u Protein Sci (2019)

Introduction: Drug Resistance

od Yilmaz, Nese Kurt, Schiffer, Celia A.
Izdano u Chem Rev (2021)

Structure-Based Prediction of Potential Binding and Nonbinding Peptides to HIV-1 Protease

od Kurt, Nese, Haliloglu, Turkan, Schiffer, Celia A.
Izdano 2003

New Approaches to HIV Protease Inhibitor Drug Design II: Testing the substrate envelope hypothesis to avoid drug resistance and discover robust inhibitors

od Nalam, Madhavi N. L., Schiffer, Celia A.
Izdano 2008

Rationale for More Diverse Inhibitors in Competition with Substrates in HIV-1 Protease

od Ozer, Nevra, Schiffer, Celia A., Haliloglu, Turkan
Izdano 2010

Dynamics of Preferential Substrate Recognition in HIV-1 Protease: Redefining the Substrate Envelope

od Özen, Ayşegül, Haliloğlu, Türkan, Schiffer, Celia A.
Izdano 2011

HIV-1 Protease and Substrate Coevolution Validates the Substrate Envelope As the Substrate Recognition Pattern

od Özen, Ayşegül, Haliloğlu, Türkan, Schiffer, Celia A.
Izdano 2012

Improving the Resistance Profile of Hepatitis C NS3/4A Inhibitors: Dynamic Substrate Envelope Guided Design

od Özen, Ayşegül, Sherman, Woody, Schiffer, Celia A.
Izdano 2013

Structural Analysis of Asunaprevir Resistance in HCV NS3/4A Protease

od Soumana, Djadé I., Ali, Akbar, Schiffer, Celia A.
Izdano u ACS Chem Biol (2014)

Improving Viral Protease Inhibitors to Counter Drug Resistance

od Yilmaz, Nese Kurt, Swanstrom, Ronald, Schiffer, Celia A.
Izdano u Trends Microbiol (2016)

Target-Specific Prediction of Ligand Affinity with Structure-Based Interaction Fingerprints

od Leidner, Florian, Kurt Yilmaz, Nese, Schiffer, Celia A.
Izdano u J Chem Inf Model (2019)

NMR and MD studies combined to elucidate inhibitor and water interactions of HIV-1 protease and their modulations with resistance mutations

od Ishima, Rieko, Kurt-Yilmaz, Nese, Schiffer, Celia A.
Izdano u J Biomol NMR (2019)

Deciphering complex mechanisms of resistance and loss of potency through coupled molecular dynamics and machine learning

od Leidner, Florian, Yilmaz, Nese Kurt, Schiffer, Celia A.
Izdano u J Chem Theory Comput (2021)

Human Immunodeficiency Virus Type 1 Protease-Correlated Cleavage Site Mutations Enhance Inhibitor Resistance

od Kolli, Madhavi, Stawiski, Eric, Chappey, Colombe, Schiffer, Celia A.
Izdano 2009

Drug-resistant HIV-1 protease regains functional dynamics through cleavage site coevolution

od Özer, Nevra, Özen, Ayşegül, Schiffer, Celia A, Haliloğlu, Türkan
Izdano u Evol Appl (2015)

Quantitative comparison of errors in (15)N transverse relaxation rates measured using various CPMG phasing schemes

od Myint, Wazo, Cai, Yufeng, Schiffer, Celia A., Ishima, Rieko
Izdano u J Biomol NMR (2012)