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Resilience to Resistance of HIV-1 Protease Inhibitors: Profile of Darunavir

The current effectiveness of HAART in the management of HIV infection is compromised by the emergence of extensively cross-resistant strains of HIV-1, requiring a significant need for new therapeutic agents. Due to its crucial role in viral maturation and therefore HIV-1 replication and infectivity,...

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Bibliographic Details
Main Authors: Lefebvre, Eric, Schiffer, Celia A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699666/
https://ncbi.nlm.nih.gov/pubmed/18820715
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