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The Higher Barrier of Darunavir and Tipranavir Resistance for HIV-1 Protease
Darunavir and tipranavir are two inhibitors that are active against multi-drug resistant (MDR) HIV-1 protease variants. In this study, the in vitro inhibitory efficacy was tested against a MDR HIV-1 protease variant, MDR 769 82T, containing the drug resistance mutations of 46L/54V/82T/84V/90M. Cryst...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188455/ https://ncbi.nlm.nih.gov/pubmed/21871444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.08.045 |
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