The Higher Barrier of Darunavir and Tipranavir Resistance for HIV-1 Protease

Por Wang, Yong, Liu, Zhigang, Brunzelle, Joseph S., Kovari, Iulia A., Dewdney, Tamaria G., Reiter, Samuel J., Kovari, Ladislau C.
Publicado em 2011

Higher Desolvation Energy Reduces Molecular Recognition in Multi-Drug Resistant HIV-1 Protease

Por Wang, Yong, Dewdney, Tamaria G., Liu, Zhigang, Reiter, Samuel J., Brunzelle, Joseph S., Kovari, Iulia A., Kovari, Ladislau C.
Publicado em 2012

Conserved Hydrogen Bonds and Water Molecules in MDR HIV-1 Protease Substrate Complexes

Por Liu, Zhigang, Wang, Yong, Yedidi, Ravikiran S., Dewdney, Tamaria G., Reiter, Samuel J., Brunzelle, Joseph S., Kovari, Iulia A., Kovari, Ladislau C.
Publicado no Biochem Biophys Res Commun (2012)

Crystallographic study of multi-drug resistant HIV-1 protease Lopinavir complex: mechanism of drug recognition and resistance

Por Liu, Zhigang, Yedidi, Ravikiran S., Wang, Yong, Dewdney, Tamaria G., Reiter, Samuel J., Brunzelle, Joseph S., Kovari, Iulia A., Kovari, Ladislau C.
Publicado no Biochem Biophys Res Commun (2013)

Cryo-EM reveals a novel octameric integrase structure for β-retroviral intasome function

Por Ballandras-Colas, Allison, Brown, Monica, Cook, Nicola J., Dewdney, Tamaria G., Demeler, Borries, Cherepanov, Peter, Lyumkis, Dmitry, Engelman, Alan N.
Publicado no Nature (2016)

The L33F darunavir resistance mutation acts as a molecular anchor reducing the flexibility of the HIV-1 protease 30s and 80s loops

Por Kuiper, Benjamin D., Keusch, Bradley J., Dewdney, Tamaria G., Chordia, Poorvi, Ross, Kyla, Brunzelle, Joseph S., Kovari, Iulia A., MacArthur, Rodger, Salimnia, Hossein, Kovari, Ladislau C.
Publicado no Biochem Biophys Rep (2015)

Structural Insight into HIV-1 Restriction by MxB

Por Fribourgh, Jennifer L., Nguyen, Henry C., Matreyek, Kenneth A., Alvarez, Frances Joan D., Summers, Brady J., Dewdney, Tamaria G., Aiken, Christopher, Zhang, Peijun, Engelman, Alan, Xiong, Yong
Publicado no Cell Host Microbe (2014)