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Structure-Based Prediction of Potential Binding and Nonbinding Peptides to HIV-1 Protease

HIV-1 protease is a major drug target against AIDS as it permits viral maturation by processing the gag and pol polyproteins of the virus. The cleavage sites in these polyproteins do not have obvious sequence homology or a binding motif and the specificity of the protease is not easily determined. W...

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Detalles Bibliográficos
Main Authors: Kurt, Nese, Haliloglu, Turkan, Schiffer, Celia A.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303207/
https://ncbi.nlm.nih.gov/pubmed/12885633
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