Aprenda em 14 dias MCSE windows NT server 4 /

Autor Schaer, David.
Vydáno 1998.

Modulation of GITR for cancer immunotherapy

Autor Schaer, David A, Murphy, Judith T, Wolchok, Jedd D
Vydáno 2012

Hiding the road signs that lead to tumor immunity

Autor Schaer, David A., Lesokhin, Alexander M., Wolchok, Jedd D.
Vydáno 2011

Targeting tumor-necrosis factor receptor pathways for tumor immunotherapy

Autor Schaer, David A, Hirschhorn-Cymerman, Daniel, Wolchok, Jedd D
Vydáno 2014

Modulation of CTLA-4 and GITR for Cancer Immunotherapy

Autor Avogadri, Francesca, Yuan, Jianda, Yang, Arvin, Schaer, David, Wolchok, Jedd D.
Vydáno 2011

Blockade of Treg derived TGF-β abrogates suppression of effector T cell function within the tumor microenvironment

Autor Budhu, Sadna, Schaer, David, Li, Yongbiao, Houghton, Alan, Silverstein, Samuel, Merghoub, Taha, Wolchok, Jedd
Vydáno 2013

Impairment of Treg suppression by GITR ligation is effective selectively in the context of a pro-inflammatory tumor microenvironment

Autor Zappasodi, Roberta, Budhu, Sadna, Schaer, David, Yang, Xia, Zhong, Hong, Merghoub, Taha, Wolchok, Jedd D
Vydáno v J Immunother Cancer (2014)

Blockade of surface bound TGF-β abrogates Treg suppression of effector T cell function within the tumor microenvironment

Autor Budhu, Sadna, Schaer, David, Li, Yongbiao, Houghton, Alan, Silverstein, Samuel, Merghoub, Taha, Wolchok, Jedd D
Vydáno v J Immunother Cancer (2014)

Timing of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy

Autor Holmgaard, Rikke B., Brachfeld, Alexandra, Gasmi, Billel, Jones, David R., Mattar, Marissa, Doman, Thompson, Murphy, Mary, Schaer, David, Wolchok, Jedd D., Merghoub, Taha
Vydáno v Oncoimmunology (2016)

GITR Pathway Activation Abrogates Tumor Immune Suppression Through Loss of Regulatory T cell Lineage Stability

Autor Schaer, David A., Budhu, Sadna, Liu, Cailian, Bryson, Campbell, Malandro, Nicole, Cohen, Adam, Zhong, Hong, Yang, Xia, Houghton, Alan N., Merghoub, Taha, Wolchok, Jedd D.
Vydáno 2013

Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment

Autor Budhu, Sadna, Schaer, David A., Li, Yongbiao, Toledo-Crow, Ricardo, Panageas, Katherine, Yang, Xia, Zhong, Hong, Houghton, Alan N., Silverstein, Samuel C., Merghoub, Taha, Wolchok, Jedd D.
Vydáno v Sci Signal (2017)

Detection of Intra-Tumor Self Antigen Recognition during Melanoma Tumor Progression in Mice Using Advanced Multimode Confocal/Two Photon Microscope

Autor Schaer, David A., Li, Yongbiao, Merghoub, Taha, Rizzuto, Gabrielle A., Shemesh, Amos, Cohen, Adam D., Li, Yanyun, Avogadri, Francesca, Toledo-Crow, Ricardo, Houghton, Alan N., Wolchok, Jedd D.
Vydáno 2011

Targeting the TGFβ pathway with galunisertib, a TGFβRI SMI, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint i...

Autor Schaer, David, Li, Yanxia, Castaneda, Stephen, Inigo, Ivan, Surguladze, David, Xu, Xiaohong, Nugent, Desiree, Murphy, Mary, Hall, Gerald, Benhadji, Karim, Guba, Susan, Li, Yiwen, Kalos, Michael, Driscoll, Kyla
Vydáno v J Immunother Cancer (2015)

FcγRIIIa-dependent IFN-γ release in whole blood assay is predictive of therapeutic IgG1 antibodies safety

Autor Alakhras, Nada S., Qiu, Jiabin, Rocha, Guilherme V., Witcher, Derrick R., Koester, Anja, You, Jinsam, Schaer, David A., Holmgaard, Rikke B., Driscoll, Kyla, Willy, Jeffrey A., Malherbe, Laurent P.
Vydáno v MAbs (2018)

Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma

Autor Benezra, Miriam, Penate-Medina, Oula, Zanzonico, Pat B., Schaer, David, Ow, Hooisweng, Burns, Andrew, DeStanchina, Elisa, Longo, Valerie, Herz, Erik, Iyer, Srikant, Wolchok, Jedd, Larson, Steven M., Wiesner, Ulrich, Bradbury, Michelle S.
Vydáno 2011

Agonist Anti-GITR Monoclonal Antibody Induces Melanoma Tumor Immunity in Mice by Altering Regulatory T Cell Stability and Intra-Tumor Accumulation

Autor Cohen, Adam D., Schaer, David A., Liu, Cailian, Li, Yanyun, Hirschhorn-Cymmerman, Daniel, Kim, Soo Chong, Diab, Adi, Rizzuto, Gabrielle, Duan, Fei, Perales, Miguel A., Merghoub, Taha, Houghton, Alan N., Wolchok, Jedd D.
Vydáno 2010

Rational design of anti-GITR-based combination immunotherapy

Autor Zappasodi, Roberta, Sirard, Cynthia, Li, Yanyun, Budhu, Sadna, Abu-Akeel, Moshen, Liu, Cailian, Yang, Xia, Zhong, Hong, Newman, Walter, Qi, Jingjing, Wong, Philip, Schaer, David, Koon, Henry, Velcheti, Vamsidhar, Postow, Michael A., Callahan, Margaret K., Wolchok, Jedd D., Merghoub, Taha
Vydáno v Nat Med (2019)

Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combinat...

Autor Holmgaard, Rikke B., Schaer, David A., Li, Yanxia, Castaneda, Stephen P., Murphy, Mary Y., Xu, Xiaohong, Inigo, Ivan, Dobkin, Julie, Manro, Jason R., Iversen, Philip W., Surguladze, David, Hall, Gerald E., Novosiadly, Ruslan D., Benhadji, Karim A., Plowman, Gregory D., Kalos, Michael, Driscoll, Kyla E.
Vydáno v J Immunother Cancer (2018)

Peripheral blood and tumor biomarkers in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab

Autor Callahan, Margaret K, Horak, Christine E, Curran, Michael A, Hollman, Travis, Schaer, David A, Yuan, Jianda, Lesokhin, Alexander M, Kitano, Shigehisa, Hong, Quan, Ariyan, Charlotte E, Busam, Klaus J, Feely, William, Jure-Kunkel, Maria, Grosso, Joseph, Simon, Jason S, Korman, Alan J, Wigginton, Jon M, Gupta, Ashok K, Zhang, Xiaoling, Phillips, Therese, Simmons, Pauline, Sznol, Mario, Wolchok, Jedd D
Vydáno 2013

Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody

Autor Gombos, Randi B., Gonzalez, Ana, Manrique, Mariana, Chand, Dhan, Savitsky, David, Morin, Benjamin, Breous-Nystrom, Ekaterina, Dupont, Christopher, Ward, Rebecca A., Mundt, Cornelia, Duckless, Benjamin, Tang, Hao, Findeis, Mark A., Schuster, Andrea, Waight, Jeremy D., Underwood, Dennis, Clarke, Christopher, Ritter, Gerd, Merghoub, Taha, Schaer, David, Wolchok, Jedd D., van Dijk, Marc, Buell, Jennifer S., Cuillerot, Jean-Marie, Stein, Robert, Drouin, Elise E., Wilson, Nicholas S.
Vydáno v PLoS One (2018)