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Modulation of CTLA-4 and GITR for Cancer Immunotherapy

The rational manipulation of antigen-specific T cells to reignite a tumor-specific immune response in cancer patients is a challenge for cancer immunotherapy. Targeting coinhibitory and costimulatory T cell receptors with specific antibodies in cancer patients is an emerging approach to T cell manip...

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Hlavní autoři: Avogadri, Francesca, Yuan, Jianda, Yang, Arvin, Schaer, David, Wolchok, Jedd D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060248/
https://ncbi.nlm.nih.gov/pubmed/20563707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2010_49
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