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At the Bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy

It is increasingly appreciated that cancers are recognized by the immune system, and under some circumstances, the immune system may control or even eliminate tumors. The modulation of signaling via coinhibitory or costimulatory receptors expressed on T cells has proven to be a potent way to amplify...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Callahan, Margaret K., Wolchok, Jedd D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Leukocyte Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051187/
https://ncbi.nlm.nih.gov/pubmed/23667165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1212631
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