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At the Bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy

It is increasingly appreciated that cancers are recognized by the immune system, and under some circumstances, the immune system may control or even eliminate tumors. The modulation of signaling via coinhibitory or costimulatory receptors expressed on T cells has proven to be a potent way to amplify...

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Detalhes bibliográficos
Main Authors: Callahan, Margaret K., Wolchok, Jedd D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051187/
https://ncbi.nlm.nih.gov/pubmed/23667165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1212631
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