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At the Bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy
Tumors can avoid immune surveillance by stimulating immune inhibitory receptors that function to turn off established immune responses. By blocking the ability of tumors to stimulate inhibitory receptors on T cells, sustained, anti-tumor immune responses can be generated in animals. Thus, therapeuti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685017/ https://ncbi.nlm.nih.gov/pubmed/23625198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1212621 |
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