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CTLA-4 and PD-1 Pathway Blockade: Combinations in the Clinic
Checkpoint blocking antibodies targeting regulatory molecules on T cells such as CTLA-4 and PD-1 have reinvigorated the field of cancer immunotherapy. These agents have demonstrated clinical activity across a variety of tumor types. Now that safety and clinical activity has been demonstrated in the...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295550/ https://ncbi.nlm.nih.gov/pubmed/25642417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00385 |
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