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PD-L1 (B7-H1) and PD-1 Pathway Blockade for Cancer Therapy: Mechanisms, Response Biomarkers and Combinations
PD-L1 and PD-1 (PD) pathway blockade is a highly promising therapy and has elicited durable anti-tumor responses and long-term remissions in a subset of patients with a broad spectrum of cancers. How to improve, widen, and predict the clinical response to anti-PD therapy is a central theme in the fi...
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| Published in: | Sci Transl Med |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4859220/ https://ncbi.nlm.nih.gov/pubmed/26936508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad7118 |
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