Insulin-like Growth Factor Binding Protein-4 Differentially Inhibits Growth Factor-induced Angiogenesis

Por Contois, Liangru W., Nugent, Desiree P., Caron, Jennifer M., Cretu, Alexandra, Tweedie, Eric, Akalu, Abebe, Liebes, Leonard, Friesel, Robert, Rosen, Clifford, Vary, Calvin, Brooks, Peter C.
Publicado em 2012

Neutralizing murine TGFβR2 promotes a differentiated tumor cell phenotype and inhibits pancreatic cancer metastasis

Por Ostapoff, Katherine T., Cenik, Bercin Kutluk, Wang, Miao, Ye, Risheng, Xu, Xiaohong, Nugent, Desiree, Hagopian, Moriah M., Topalovski, Mary, Rivera, Lee B., Carroll, Kyla D., Brekken, Rolf A.
Publicado em 2014

Targeting the TGFβ pathway with galunisertib, a TGFβRI SMI, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint i...

Por Schaer, David, Li, Yanxia, Castaneda, Stephen, Inigo, Ivan, Surguladze, David, Xu, Xiaohong, Nugent, Desiree, Murphy, Mary, Hall, Gerald, Benhadji, Karim, Guba, Susan, Li, Yiwen, Kalos, Michael, Driscoll, Kyla
Publicado no J Immunother Cancer (2015)