Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay

Por Linares, María, Viera, Sara, Crespo, Benigno, Franco, Virginia, Gómez-Lorenzo, María G., Jiménez-Díaz, María Belén, Angulo-Barturen, Íñigo, Sanz, Laura María, Gamo, Francisco-Javier
Publicado no Malar J (2015)

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

Por Le Bihan, Amélie, de Kanter, Ruben, Angulo-Barturen, Iñigo, Binkert, Christoph, Boss, Christoph, Brun, Reto, Brunner, Ralf, Buchmann, Stephan, Burrows, Jeremy, Dechering, Koen J., Delves, Michael, Ewerling, Sonja, Ferrer, Santiago, Fischli, Christoph, Gamo–Benito, Francisco Javier, Gnädig, Nina F., Heidmann, Bibia, Jiménez-Díaz, María Belén, Leroy, Didier, Martínez, Maria Santos, Meyer, Solange, Moehrle, Joerg J., Ng, Caroline L., Noviyanti, Rintis, Ruecker, Andrea, Sanz, Laura María, Sauerwein, Robert W., Scheurer, Christian, Schleiferboeck, Sarah, Sinden, Robert, Snyder, Christopher, Straimer, Judith, Wirjanata, Grennady, Marfurt, Jutta, Price, Ric N., Weller, Thomas, Fischli, Walter, Fidock, David A., Clozel, Martine, Wittlin, Sergio
Publicado no PLoS Med (2016)

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate

Por Hameed P., Shahul, Solapure, Suresh, Patil, Vikas, Henrich, Philipp P., Magistrado, Pamela A., Bharath, Sowmya, Murugan, Kannan, Viswanath, Pavithra, Puttur, Jayashree, Srivastava, Abhishek, Bellale, Eknath, Panduga, Vijender, Shanbag, Gajanan, Awasthy, Disha, Landge, Sudhir, Morayya, Sapna, Koushik, Krishna, Saralaya, Ramanatha, Raichurkar, Anandkumar, Rautela, Nikhil, Roy Choudhury, Nilanjana, Ambady, Anisha, Nandishaiah, Radha, Reddy, Jitendar, Prabhakar, K. R., Menasinakai, Sreenivasaiah, Rudrapatna, Suresh, Chatterji, Monalisa, Jiménez-Díaz, María Belén, Martínez, María Santos, Sanz, Laura María, Coburn-Flynn, Olivia, Fidock, David A., Lukens, Amanda K., Wirth, Dyann F., Bandodkar, Balachandra, Mukherjee, Kakoli, McLaughlin, Robert E., Waterson, David, Rosenbrier-Ribeiro, Lyn, Hickling, Kevin, Balasubramanian, V., Warner, Peter, Hosagrahara, Vinayak, Dudley, Adam, Iyer, Pravin S., Narayanan, Shridhar, Kavanagh, Stefan, Sambandamurthy, Vasan K.
Publicado no Nat Commun (2015)

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase

Por Paquet, Tanya, Le Manach, Claire, Cabrera, Diego González, Younis, Yassir, Henrich, Philipp P., Abraham, Tara S., Lee, Marcus C. S., Basak, Rajshekhar, Ghidelli-Disse, Sonja, Lafuente-Monasterio, María José, Bantscheff, Marcus, Ruecker, Andrea, Blagborough, Andrew M., Zakutansky, Sara E., Zeeman, Anne-Marie, White, Karen L., Shackleford, David M., Mannila, Janne, Morizzi, Julia, Scheurer, Christian, Angulo-Barturen, Iñigo, Martínez, María Santos, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Reader, Janette, Botha, Mariette, Dechering, Koen J., Sauerwein, Robert W., Tungtaeng, Anchalee, Vanachayangkul, Pattaraporn, Lim, Chek Shik, Burrows, Jeremy, Witty, Michael J., Marsh, Kennan C., Bodenreider, Christophe, Rochford, Rosemary, Solapure, Suresh M., Jiménez-Díaz, María Belén, Wittlin, Sergio, Charman, Susan A., Donini, Cristina, Campo, Brice, Birkholtz, Lyn-Marie, Hanson, Kirsten K., Drewes, Gerard, Kocken, Clemens H. M., Delves, Michael J., Leroy, Didier, Fidock, David A., Waterson, David, Street, Leslie J., Chibale, Kelly
Publicado no Sci Transl Med (2017)

A novel multiple-stage antimalarial agent that inhibits protein synthesis

Por Baragaña, Beatriz, Hallyburton, Irene, Lee, Marcus C. S., Norcross, Neil R., Grimaldi, Raffaella, Otto, Thomas D., Proto, William R., Blagborough, Andrew M., Meister, Stephan, Wirjanata, Grennady, Ruecker, Andrea, Upton, Leanna M., Abraham, Tara S., Almeida, Mariana J., Pradhan, Anupam, Porzelle, Achim, Martínez, María Santos, Bolscher, Judith M., Woodland, Andrew, Norval, Suzanne, Zuccotto, Fabio, Thomas, John, Simeons, Frederick, Stojanovski, Laste, Osuna-Cabello, Maria, Brock, Paddy M., Churcher, Tom S., Sala, Katarzyna A., Zakutansky, Sara E., Jiménez-Díaz, María Belén, Sanz, Laura Maria, Riley, Jennifer, Basak, Rajshekhar, Campbell, Michael, Avery, Vicky M., Sauerwein, Robert W, Dechering, Koen J., Noviyanti, Rintis, Campo, Brice, Frearson, Julie A., Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago, Gamo, Francisco Javier, Wyatt, Paul G., Leroy, Didier, Siegl, Peter, Delves, Michael J., Kyle, Dennis E., Wittlin, Sergio, Marfurt, Jutta, Price, Ric N., Sinden, Robert E., Winzeler, Elizabeth, Charman, Susan A., Bebrevska, Lidiya, Gray, David W., Campbell, Simon, Fairlamb, Alan H., Willis, Paul, Rayner, Julian C., Fidock, David A., Read, Kevin D., Gilbert, Ian H.
Publicado no Nature (2015)