The Cardiovascular Physiology and Pharmacology of Endothelin-1

Tekijä Thorin, Eric, Clozel, Martine
Julkaistu 2010

Pharmacokinetics and pharmacodynamics of tezosentan, an intravenous dual endothelin receptor antagonist, following chronic infusion in healthy subjects

Tekijä Dingemanse, Jasper, Clozel, Martine, van Giersbergen, Paul L M
Julkaistu 2002

Slow Receptor Dissociation Kinetics Differentiate Macitentan from Other Endothelin Receptor Antagonists in Pulmonary Arterial Smooth Muscle Cells

Tekijä Gatfield, John, Mueller Grandjean, Celia, Sasse, Thomas, Clozel, Martine, Nayler, Oliver
Julkaistu 2012

Vascular Effects of Endothelin Receptor Antagonists Depends on Their Selectivity for ET(A) Versus ET(B) Receptors and on the Functionality of Endothelial ET(B) Receptors

Tekijä Iglarz, Marc, Steiner, Pauline, Wanner, Daniel, Rey, Markus, Hess, Patrick, Clozel, Martine
Julkaisussa J Cardiovasc Pharmacol (2015)

Desensitization by Progressive Up-Titration Prevents First-Dose Effects on the Heart: Guinea Pig Study with Ponesimod, a Selective S1P(1) Receptor Modulator

Tekijä Rey, Markus, Hess, Patrick, Clozel, Martine, Delahaye, Stéphane, Gatfield, John, Nayler, Oliver, Steiner, Beat
Julkaistu 2013

Therapeutic Potential of Ponesimod Alone and in Combination with Dimethyl Fumarate in Experimental Models of Multiple Sclerosis

Tekijä Pouzol, Laetitia, Piali, Luca, Bernard, Claude CA, Martinic, Marianne M., Steiner, Beat, Clozel, Martine
Julkaisussa Innov Clin Neurosci (2019)

Cadazolid Does Not Promote Intestinal Colonization of Vancomycin-Resistant Enterococci in Mice

Tekijä Seiler, Peter, Enderlin-Paput, Michel, Pfaff, Philippe, Weiss, Maria, Ritz, Daniel, Clozel, Martine, Locher, Hans H.
Julkaisussa Antimicrob Agents Chemother (2015)

Therapeutic Use of a Selective S1P(1) Receptor Modulator Ponesimod in Autoimmune Diabetes

Tekijä You, Sylvaine, Piali, Luca, Kuhn, Chantal, Steiner, Beat, Sauvaget, Virginia, Valette, Fabrice, Clozel, Martine, Bach, Jean-François, Chatenoud, Lucienne
Julkaistu 2013

Tezosentan, a Novel Endothelin Receptor Antagonist, Markedly Reduces Rat Hepatic Ischemia and Reperfusion Injury in Three Different Models

Tekijä Farmer, Douglas G., Kaldas, Fady, Anselmo, Dean, Katori, Masamichi, Shen, Xiu-Da, Lassman, Charles, Kaldas, Marian, Clozel, Martine, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy
Julkaistu 2008

The reversible P2Y(12) antagonist ACT‐246475 causes significantly less blood loss than ticagrelor at equivalent antithrombotic efficacy in rat

Tekijä Rey, Markus, Kramberg, Markus, Hess, Patrick, Morrison, Keith, Ernst, Roland, Haag, Franck, Weber, Edgar, Clozel, Martine, Baumann, Martine, Caroff, Eva, Hubler, Francis, Riederer, Markus A., Steiner, Beat
Julkaisussa Pharmacol Res Perspect (2017)

Cenerimod, a novel selective S1P(1) receptor modulator with unique signaling properties

Tekijä Piali, Luca, Birker‐Robaczewska, Magdalena, Lescop, Cyrille, Froidevaux, Sylvie, Schmitz, Nicole, Morrison, Keith, Kohl, Christopher, Rey, Markus, Studer, Rolf, Vezzali, Enrico, Hess, Patrick, Clozel, Martine, Steiner, Beat, Bolli, Martin H., Nayler, Oliver
Julkaisussa Pharmacol Res Perspect (2017)

CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based...

Tekijä Ng, Caroline L., Siciliano, Giulia, Lee, Marcus C. S., de Almeida, Mariana J., Corey, Victoria C., Bopp, Selina E., Bertuccini, Lucia, Wittlin, Sergio, Kasdin, Rachel G., Le Bihan, Amélie, Clozel, Martine, Winzeler, Elizabeth A., Alano, Pietro, Fidock, David A.
Julkaisussa Mol Microbiol (2016)

Comparison of Macitentan and Bosentan on Right Ventricular Remodeling in a Rat Model of Non-vasoreactive Pulmonary Hypertension

Tekijä Iglarz, Marc, Landskroner, Kyle, Bauer, Yasmina, Vercauteren, Magali, Rey, Markus, Renault, Berengère, Studer, Rolf, Vezzali, Enrico, Freti, Diego, Hadana, Hakim, Schläpfer, Manuela, Cattaneo, Christophe, Bortolamiol, Céline, Weber, Edgar, Whitby, Brian R., Delahaye, Stéphane, Wanner, Daniel, Steiner, Pauline, Nayler, Oliver, Hess, Patrick, Clozel, Martine
Julkaisussa J Cardiovasc Pharmacol (2015)

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

Tekijä Le Bihan, Amélie, de Kanter, Ruben, Angulo-Barturen, Iñigo, Binkert, Christoph, Boss, Christoph, Brun, Reto, Brunner, Ralf, Buchmann, Stephan, Burrows, Jeremy, Dechering, Koen J., Delves, Michael, Ewerling, Sonja, Ferrer, Santiago, Fischli, Christoph, Gamo–Benito, Francisco Javier, Gnädig, Nina F., Heidmann, Bibia, Jiménez-Díaz, María Belén, Leroy, Didier, Martínez, Maria Santos, Meyer, Solange, Moehrle, Joerg J., Ng, Caroline L., Noviyanti, Rintis, Ruecker, Andrea, Sanz, Laura María, Sauerwein, Robert W., Scheurer, Christian, Schleiferboeck, Sarah, Sinden, Robert, Snyder, Christopher, Straimer, Judith, Wirjanata, Grennady, Marfurt, Jutta, Price, Ric N., Weller, Thomas, Fischli, Walter, Fidock, David A., Clozel, Martine, Wittlin, Sergio
Julkaisussa PLoS Med (2016)