Therapeutic Use of a Selective S1P(1) Receptor Modulator Ponesimod in Autoimmune Diabetes

In the present study, we investigated the therapeutic potential of a selective S1P(1) receptor modulator, ponesimod, to protect and reverse autoimmune diabetes in non-obese diabetic (NOD) mice. Ponesimod was administered orally to NOD mice starting at 6, 10, 13 and 16 weeks of age up to 35 weeks of...

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Bibliografiske detaljer
Main Authors: You, Sylvaine, Piali, Luca, Kuhn, Chantal, Steiner, Beat, Sauvaget, Virginia, Valette, Fabrice, Clozel, Martine, Bach, Jean-François, Chatenoud, Lucienne
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811978/
https://ncbi.nlm.nih.gov/pubmed/24204793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077296
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