First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

por Moehrle, Joerg J, Duparc, Stephan, Siethoff, Christoph, Giersbergen, Paul L M, Craft, J Carl, Arbe-Barnes, Sarah, Charman, Susan A, Gutierrez, Maria, Wittlin, Sergio, Vennerstrom, Jonathan L
Publicado 2013

Increased stress associated with head-out plethysmography testing can exacerbate respiratory effects and lead to mortality in rats

por Lynch, James J., Rossignol, Emilie, Moehrle, Joerg J., Van Vleet, Terry R., Marsh, Kennan C., Parman, Toufan, Mirsalis, Jon, Ottinger, Sean E., Segreti, Jason A., Rao, Mohan, Mittelstadt, Scott W.
Publicado en J Pharmacol Toxicol Methods (2019)

Liver Function Test Abnormalities in Experimental and Clinical Plasmodium vivax Infection

por Odedra, Anand, Webb, Lachlan, Marquart, Louise, Britton, Laurence J., Chalon, Stephan, Moehrle, Joerg J., Anstey, Nicholas M., William, Timothy, Grigg, Matthew J., Lalloo, David G., Barber, Bridget E., McCarthy, James S.
Publicado en Am J Trop Med Hyg (2020)

Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies

por Woolley, Stephen D., Fernandez, Melissa, Rebelo, Maria, Llewellyn, Stacey A., Marquart, Louise, Amante, Fiona H., Jennings, Helen E., Webster, Rebecca, Trenholme, Katharine, Chalon, Stephan, Moehrle, Joerg J., McCarthy, James S., Barber, Bridget E.
Publicado en Malar J (2021)

A Plasmodium vivax experimental human infection model for evaluating efficacy of interventions

por Collins, Katharine A., Wang, Claire Y.T., Adams, Matthew, Mitchell, Hayley, Robinson, Greg J., Rampton, Melanie, Elliott, Suzanne, Odedra, Anand, Khoury, David, Ballard, Emma, Shelper, Todd B., Lucantoni, Leonardo, Avery, Vicky M., Chalon, Stephan, Moehrle, Joerg J., McCarthy, James S.
Publicado en J Clin Invest (2020)

An in vitro toolbox to accelerate anti-malarial drug discovery and development

por Charman, Susan A., Andreu, Alice, Barker, Helena, Blundell, Scott, Campbell, Anna, Campbell, Michael, Chen, Gong, Chiu, Francis C. K., Crighton, Elly, Katneni, Kasiram, Morizzi, Julia, Patil, Rahul, Pham, Thao, Ryan, Eileen, Saunders, Jessica, Shackleford, David M., White, Karen L., Almond, Lisa, Dickins, Maurice, Smith, Dennis A., Moehrle, Joerg J., Burrows, Jeremy N., Abla, Nada
Publicado en Malar J (2020)

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

por Le Bihan, Amélie, de Kanter, Ruben, Angulo-Barturen, Iñigo, Binkert, Christoph, Boss, Christoph, Brun, Reto, Brunner, Ralf, Buchmann, Stephan, Burrows, Jeremy, Dechering, Koen J., Delves, Michael, Ewerling, Sonja, Ferrer, Santiago, Fischli, Christoph, Gamo–Benito, Francisco Javier, Gnädig, Nina F., Heidmann, Bibia, Jiménez-Díaz, María Belén, Leroy, Didier, Martínez, Maria Santos, Meyer, Solange, Moehrle, Joerg J., Ng, Caroline L., Noviyanti, Rintis, Ruecker, Andrea, Sanz, Laura María, Sauerwein, Robert W., Scheurer, Christian, Schleiferboeck, Sarah, Sinden, Robert, Snyder, Christopher, Straimer, Judith, Wirjanata, Grennady, Marfurt, Jutta, Price, Ric N., Weller, Thomas, Fischli, Walter, Fidock, David A., Clozel, Martine, Wittlin, Sergio
Publicado en PLoS Med (2016)