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Cenerimod, a novel selective S1P(1) receptor modulator with unique signaling properties

Sphingosine‐1‐phosphate receptor 1 (S1P(1)) modulators sequester circulating lymphocytes within lymph nodes, thereby preventing potentially pathogenic autoimmune cells from exiting into the blood stream and reaching inflamed tissues. S1P(1) receptor modulation may thus offer potential to treat vario...

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Bibliografski detalji
Izdano u:Pharmacol Res Perspect
Glavni autori: Piali, Luca, Birker‐Robaczewska, Magdalena, Lescop, Cyrille, Froidevaux, Sylvie, Schmitz, Nicole, Morrison, Keith, Kohl, Christopher, Rey, Markus, Studer, Rolf, Vezzali, Enrico, Hess, Patrick, Clozel, Martine, Steiner, Beat, Bolli, Martin H., Nayler, Oliver
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723703/
https://ncbi.nlm.nih.gov/pubmed/29226621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.370
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