Transient trimethylaminuria related to menstruation

Por Shimizu, Makiko, Cashman, John R, Yamazaki, Hiroshi
Publicado em 2007

Dataset for genotyping validation of cytochrome P450 2A6 whole-gene deletion (CYP2A6*4) by real-time polymerase chain reaction platforms

Por Shimizu, Makiko, Koyama, Tomoki, Kishimoto, Izumi, Yamazaki, Hiroshi
Publicado no Data Brief (2015)

Potential impact of cytochrome P450 3A5 in human liver on drug interactions with triazoles

Por Yamazaki, Hiroshi, Nakamoto, Minako, Shimizu, Makiko, Murayama, Norie, Niwa, Toshiro
Publicado em 2010

Trimethylamine generation in patients receiving hemodialysis treated with l-carnitine

Por Ozasa, Hisashi, Shimizu, Makiko, Koizumi, Ayano, Wakabayashi, Akari, Yamazaki, Hiroshi
Publicado no Clin Kidney J (2014)

Combining Chimeric Mice with Humanized Liver, Mass Spectrometry, And Physiologically-Based Pharmacokinetic Modeling in Toxicology

Por Yamazaki, Hiroshi, Suemizu, Hiroshi, Mitsui, Marina, Shimizu, Makiko, Guengerich, F. Peter
Publicado no Chem Res Toxicol (2016)

Drug Interactions of Thalidomide with Midazolam and Cyclosporine A: Heterotropic Cooperativity of Human Cytochrome P450 3A5

Por Okada, Yusuke, Murayama, Norie, Yanagida, Chihiro, Shimizu, Makiko, Guengerich, F. Peter, Yamazaki, Hiroshi
Publicado em 2009

Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population

Por Shimizu, Makiko, Allerston, Charles K, Shephard, Elizabeth A, Yamazaki, Hiroshi, Phillips, Ian R
Publicado em 2014

The CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with reduced CYP3A4 protein level and function in human liver microsomes

Por Okubo, Maho, Murayama, Norie, Shimizu, Makiko, Shimada, Tsutomu, Guengerich, F. Peter, Yamazaki, Hiroshi
Publicado em 2013

Developmental variations in metabolic capacity of flavin-containing mono-oxygenase 3 in childhood

Por Shimizu, Makiko, Denton, Travis, Kozono, Marie, Cashman, John R, Leeder, J Steven, Yamazaki, Hiroshi
Publicado em 2011

Biomonitoring of Urinary Cotinine Concentrations Associated with Plasma Levels of Nicotine Metabolites after Daily Cigarette Smoking in a Male Japanese Population

Por Nagano, Taku, Shimizu, Makiko, Kiyotani, Kazuma, Kamataki, Tetsuya, Takano, Ryohji, Murayama, Norie, Shono, Fumiaki, Yamazaki, Hiroshi
Publicado em 2010

Human Blood Concentrations of Cotinine, a Biomonitoring Marker for Tobacco Smoke, Extrapolated from Nicotine Metabolism in Rats and Humans and Physiologically Based Pharmacokinetic...

Por Yamazaki, Hiroshi, Horiuchi, Kana, Takano, Ryohji, Nagano, Taku, Shimizu, Makiko, Kitajima, Masato, Murayama, Norie, Shono, Fumiaki
Publicado em 2010

Eubacterium limosum ameliorates experimental colitis and metabolite of microbe attenuates colonic inflammatory action with increase of mucosal integrity

Por Kanauchi, Osamu, Fukuda, Masanobu, Matsumoto, Yoshiaki, Ishii, Shino, Ozawa, Toyokazu, Shimizu, Makiko, Mitsuyama, Keiichi, Andoh, Akira
Publicado em 2006

In Vivo Formation of a Glutathione Conjugate Derived from Thalidomide in Humanized uPA-NOG Mice

Por Yamazaki, Hiroshi, Suemizu, Hiroshi, Igaya, Sho, Shimizu, Makiko, Shibata, Norio, Nakamura, Masato, Chowdhury, Goutam, Guengerich, F. Peter
Publicado em 2011

Human Liver Microsomal Cytochrome P450 3A Enzymes Involved in Thalidomide 5-Hydroxylation and Formation of a Glutathione Conjugate

Por Chowdhury, Goutam, Murayama, Norie, Okada, Yusuke, Uno, Yasuhiro, Shimizu, Makiko, Shibata, Norio, Guengerich, F. Peter, Yamazaki, Hiroshi
Publicado em 2010

In vivo Formation of Dihydroxylated and Glutathione Conjugate Metabolites derived from Thalidomide and 5-Hydroxythalidomide in Humanized TK-NOG mice

Por Yamazaki, Hiroshi, Suemizu, Hiroshi, Shimizu, Makiko, Igaya, Sho, Shibata, Norio, Nakamura, Masato, Chowdhury, Goutam, Guengerich, F. Peter
Publicado em 2012

Inter-individual variations of flavin-containing monooxygenase 3 in livers from Japanese: correlation with hepatic transcription factors

Por Nagashima, Satomi, Shimizu, Makiko, Yano, Hiroshi, Murayama, Norie, Kumai, Toshio, Kobayashi, Shinichi, Guengerich, F. Peter, Yamazaki, Hiroshi
Publicado no Drug Metab Pharmacokinet (2009)

Qualitative De Novo Analysis of Full Length cDNA and Quantitative Analysis of Gene Expression for Common Marmoset (Callithrix jacchus) Transcriptomes Using Parallel Long-Read Techn...

Por Shimizu, Makiko, Iwano, Shunsuke, Uno, Yasuhiro, Uehara, Shotaro, Inoue, Takashi, Murayama, Norie, Onodera, Jun, Sasaki, Erika, Yamazaki, Hiroshi
Publicado em 2014

Assessment of Protein Binding of 5-Hydroxythalidomide Bioactivated in Humanized Mice with Human P450 3A-chromosome or Hepatocytes by Two-dimensional Electrophoresis/Accelerator Mas...

Por Yamazaki, Hiroshi, Suemizu, Hiroshi, Kazuki, Yasuhiro, Oofusa, Ken, Kuribayashi, Shunji, Shimizu, Makiko, Ninomiya, Shinichi, Horie, Toru, Shibata, Norio, Guengerich, F. Peter
Publicado no Chem Res Toxicol (2016)

Thalidomide Increases Human Hepatic Cytochrome P450 3A Enzymes by Direct Activation of Pregnane X Receptor

Por Murayama, Norie, van Beuningen, Rinie, Suemizu, Hiroshi, Guillouzo, Christiane Guguen, Shibata, Norio, Yajima, Kanako, Utoh, Masahiro, Shimizu, Makiko, Chesné, Christophe, Nakamura, Masato, Guengerich, F. Peter, Houtman, René, Yamazaki, Hiroshi
Publicado em 2014

Current status of health among workers in Japan: Results from the Japan Epidemiology Collaboration on Occupational Health Study

Por KUWAHARA, Keisuke, UEHARA, Akihiko, YAMAMOTO, Makoto, NAKAGAWA, Tohru, HONDA, Toru, YAMAMOTO, Shuichiro, OKAZAKI, Hiroko, SASAKI, Naoko, OGASAWARA, Takayuki, HORI, Ai, NISHIURA, Chihiro, MIYAMOTO, Toshiaki, KOCHI, Takeshi, EGUCHI, Masafumi, TOMITA, Kentaro, IMAI, Teppei, NISHIHARA, Akiko, NAGAHAMA, Satsue, MURAKAMI, Taizo, SHIMIZU, Makiko, KABE, Isamu, MIZOUE, Tetsuya, KUNUGITA, Naoki, SONE, Tomofumi, DOHI, Seitaro
Publicado no Ind Health (2016)