Therapeutic targeting of HES1 transcriptional programs in T-ALL

Bằng Schnell, Stephanie A., Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Belver, Laura, Xu, Luyao, Qin, Yue, Kageyama, Ryoichiro, Ferrando, Adolfo A.
Xuất bản năm Blood (2015)

Translating cancer genomics into precision medicine with artificial intelligence: applications, challenges and future perspectives

Bằng Xu, Jia, Yang, Pengwei, Xue, Shang, Sharma, Bhuvan, Sanchez-Martin, Marta, Wang, Fang, Beaty, Kirk A., Dehan, Elinor, Parikh, Baiju
Xuất bản năm Hum Genet (2019)

Small Molecule that Reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia (T-ALL)

Bằng Cantley, Alexandra M., Welsch, Matthew, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Kim, Mi-Yeon, Bauer, Andras, Ferrando, Adolfo, Stockwell, Brent R.
Được phát hành 2014

Structure and mechanisms of NT5C2 mutations driving thiopurine resistance in relapsed lymphoblastic leukemia

Bằng Dieck, Chelsea L., Tzoneva, Gannie, Forouhar, Farhad, Carpenter, Zachary, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Kirschner-Schwabe, Renate, Lew, Scott, Seetharaman, Jayaraman, Tong, Liang, Ferrando, Adolfo A.
Xuất bản năm Cancer Cell (2018)

Synergistic antileukemic therapies in NOTCH1-induced T-ALL

Bằng Sanchez-Martin, Marta, Ambesi-Impiombato, Alberto, Qin, Yue, Herranz, Daniel, Bansal, Mukesh, Girardi, Tiziana, Paietta, Elisabeth, Tallman, Martin S., Rowe, Jacob M., De Keersmaecker, Kim, Califano, Andrea, Ferrando, Adolfo A.
Xuất bản năm Proc Natl Acad Sci U S A (2017)

Comprehensive characterization of compartment specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma

Bằng Arnes, Luis, Liu, Zhaoqi, Wang, Jiguang, Maurer, H. Carlo, Sagalovskiy, Irina, Sanchez-Martin, Marta, Bommakanti, Nikhil, Garofalo, Diana C., Balderes, Dina A., Sussel, Lori, Olive, Kenneth P., Rabadan, Raul
Xuất bản năm Gut (2018)

Leukemia-specific delivery of mutant NOTCH1 targeted therapy

Bằng Roti, Giovanni, Qi, Jun, Kitara, Samuel, Sanchez-Martin, Marta, Saur Conway, Amy, Varca, Anthony C., Su, Angela, Wu, Lei, Kung, Andrew L., Ferrando, Adolfo A., Bradner, James E., Stegmaier, Kimberly
Xuất bản năm J Exp Med (2018)

CXCL12-producing vascular endothelial niches control acute T cell leukemia maintenance

Bằng Pitt, Lauren A., Tikhonova, Anastasia N., Hu, Hai, Trimarchi, Thomas, King, Bryan, Gong, Yixiao, Sanchez-Martin, Marta, Tsirigos, Aris, Littman, Dan R., Ferrando, Adolfo, Morrison, Sean J., Fooksman, David R., Aifantis, Iannis, Schwab, Susan R.
Xuất bản năm Cancer Cell (2015)

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in acute lymphoblastic leukemia

Bằng Herranz, Daniel, Ambesi-Impiombato, Alberto, Sudderth, Jessica, Sánchez-Martín, Marta, Belver, Laura, Tosello, Valeria, Xu, Luyao, Wendorff, Agnieszka A., Castillo, Mireia, Haydu, J. Erika, Márquez, Javier, Matés, José M., Kung, Andrew L., Rayport, Stephen, Cordon-Cardo, Carlos, DeBerardinis, Ralph J., Ferrando, Adolfo A.
Xuất bản năm Nat Med (2015)

The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia

Bằng Furness, Caroline L, Mansur, Marcela B, Weston, Victoria J, Ermini, Luca, van Delft, Frederik W, Jenkinson, Sarah, Gale, Rosemary, Harrison, Christine J, Pombo-de-Oliveira, Maria S, Sanchez-Martin, Marta, Ferrando, Adolfo A, Kearns, Pamela, Titley, Ian, Ford, Anthony M, Potter, Nicola E, Greaves, Mel
Xuất bản năm Leukemia (2018)

Multivalent small molecule pan-RAS inhibitors

Bằng Welsch, Matthew E., Kaplan, Anna, Chambers, Jennifer M., Stokes, Michael E., Bos, Pieter H., Zask, Arie, Zhang, Yan, Sanchez-Martin, Marta, Badgley, Michael A., Huang, Christine S., Tran, Timothy H., Akkiraju, Hemanth, Brown, Lewis M., Nandakumar, Renu, Cremers, Serge, Yang, Wan S., Tong, Liang, Olive, Kenneth P., Ferrando, Adolfo, Stockwell, Brent R.
Xuất bản năm Cell (2017)

Clonal evolution mechanisms in NT5C2 mutant relapsed acute lymphoblastic leukemia

Bằng Tzoneva, Gannie, Dieck, Chelsea L., Oshima, Koichi, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Madubata, Chioma J., Khiabanian, Hossein, Yu, Jiangyan, Waanders, Esme, Iacobucci, Ilaria, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Loh, Mignon L., Kirschner-Schwabe, Renate, Mullighan, Charles G., Rabadan, Raul, Ferrando, Adolfo A.
Xuất bản năm Nature (2018)

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

Bằng Piovan, Erich, Yu, Jiyang, Tosello, Valeria, Herranz, Daniel, Ambesi-Impiombato, Alberto, Da Silva, Ana Carolina, Sanchez-Martin, Marta, Perez-Garcia, Arianne, Rigo, Isaura, Castillo, Mireia, Indraccolo, Stefano, Cross, Justin R, de Stanchina, Elisa, Paietta, Elisabeth, Racevskis, Janis, Rowe, Jacob M, Tallman, Martin S, Basso, Giuseppe, Meijerink, Jules P, Cordon-Cardo, Carlos, Califano, Andrea, Ferrando, Adolfo A.
Được phát hành 2013

Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias

Bằng Kucine, Nicole, Marubayashi, Sachie, Bhagwat, Neha, Papalexi, Efthymia, Koppikar, Priya, Sanchez Martin, Marta, Dong, Lauren, Tallman, Marty S., Paietta, Elisabeth, Wang, Kai, He, Jie, Lipson, Doron, Stephens, Phil, Miller, Vince, Rowe, Jacob M., Teruya-Feldstein, Julie, Mullighan, Charles G., Ferrando, Adolfo A., Krivtsov, Andrei, Armstrong, Scott, Leung, Laura, Ochiana, Stefan O., Chiosis, Gabriela, Levine, Ross L., Kleppe, Maria
Xuất bản năm Blood (2015)

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

Bằng Oshima, Koichi, Khiabanian, Hossein, da Silva-Almeida, Ana C., Tzoneva, Gannie, Abate, Francesco, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Carpenter, Zachary, Penson, Alex, Perez-Garcia, Arianne, Eckert, Cornelia, Nicolas, Concepción, Balbin, Milagros, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo A.
Xuất bản năm Proc Natl Acad Sci U S A (2016)

Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias

Bằng Wang, Kai, Sanchez-Martin, Marta, Wang, Xujun, Knapp, Kristina M., Koche, Richard, Vu, Ly, Nahas, Michelle K., He, Jie, Hadler, Michael, Stein, Eytan M, Tallman, Martin S., Donahue, Amy L, Frampton, Garrett M, Lipson, Doron, Roels, Steven, Stephens, Philip J., Sanford, Eric M, Brennan, Tim, Otto, Geoff A., Yelensky, Roman, Miller, Vincent A., Kharas, Michael G., Levine, Ross L., Ferrando, Adolfo, Armstrong, Scott A., Krivtsov, Andrei V.
Xuất bản năm Leukemia (2016)