Therapeutic targeting of HES1 transcriptional programs in T-ALL

av Schnell, Stephanie A., Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Belver, Laura, Xu, Luyao, Qin, Yue, Kageyama, Ryoichiro, Ferrando, Adolfo A.
I publikationen Blood (2015)

Translating cancer genomics into precision medicine with artificial intelligence: applications, challenges and future perspectives

av Xu, Jia, Yang, Pengwei, Xue, Shang, Sharma, Bhuvan, Sanchez-Martin, Marta, Wang, Fang, Beaty, Kirk A., Dehan, Elinor, Parikh, Baiju
I publikationen Hum Genet (2019)

Small Molecule that Reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia (T-ALL)

av Cantley, Alexandra M., Welsch, Matthew, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Kim, Mi-Yeon, Bauer, Andras, Ferrando, Adolfo, Stockwell, Brent R.
Publicerad 2014

Structure and mechanisms of NT5C2 mutations driving thiopurine resistance in relapsed lymphoblastic leukemia

av Dieck, Chelsea L., Tzoneva, Gannie, Forouhar, Farhad, Carpenter, Zachary, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Kirschner-Schwabe, Renate, Lew, Scott, Seetharaman, Jayaraman, Tong, Liang, Ferrando, Adolfo A.
I publikationen Cancer Cell (2018)

Synergistic antileukemic therapies in NOTCH1-induced T-ALL

av Sanchez-Martin, Marta, Ambesi-Impiombato, Alberto, Qin, Yue, Herranz, Daniel, Bansal, Mukesh, Girardi, Tiziana, Paietta, Elisabeth, Tallman, Martin S., Rowe, Jacob M., De Keersmaecker, Kim, Califano, Andrea, Ferrando, Adolfo A.
I publikationen Proc Natl Acad Sci U S A (2017)

Comprehensive characterization of compartment specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma

av Arnes, Luis, Liu, Zhaoqi, Wang, Jiguang, Maurer, H. Carlo, Sagalovskiy, Irina, Sanchez-Martin, Marta, Bommakanti, Nikhil, Garofalo, Diana C., Balderes, Dina A., Sussel, Lori, Olive, Kenneth P., Rabadan, Raul
I publikationen Gut (2018)

Leukemia-specific delivery of mutant NOTCH1 targeted therapy

av Roti, Giovanni, Qi, Jun, Kitara, Samuel, Sanchez-Martin, Marta, Saur Conway, Amy, Varca, Anthony C., Su, Angela, Wu, Lei, Kung, Andrew L., Ferrando, Adolfo A., Bradner, James E., Stegmaier, Kimberly
I publikationen J Exp Med (2018)

CXCL12-producing vascular endothelial niches control acute T cell leukemia maintenance

av Pitt, Lauren A., Tikhonova, Anastasia N., Hu, Hai, Trimarchi, Thomas, King, Bryan, Gong, Yixiao, Sanchez-Martin, Marta, Tsirigos, Aris, Littman, Dan R., Ferrando, Adolfo, Morrison, Sean J., Fooksman, David R., Aifantis, Iannis, Schwab, Susan R.
I publikationen Cancer Cell (2015)

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in acute lymphoblastic leukemia

av Herranz, Daniel, Ambesi-Impiombato, Alberto, Sudderth, Jessica, Sánchez-Martín, Marta, Belver, Laura, Tosello, Valeria, Xu, Luyao, Wendorff, Agnieszka A., Castillo, Mireia, Haydu, J. Erika, Márquez, Javier, Matés, José M., Kung, Andrew L., Rayport, Stephen, Cordon-Cardo, Carlos, DeBerardinis, Ralph J., Ferrando, Adolfo A.
I publikationen Nat Med (2015)

The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia

av Furness, Caroline L, Mansur, Marcela B, Weston, Victoria J, Ermini, Luca, van Delft, Frederik W, Jenkinson, Sarah, Gale, Rosemary, Harrison, Christine J, Pombo-de-Oliveira, Maria S, Sanchez-Martin, Marta, Ferrando, Adolfo A, Kearns, Pamela, Titley, Ian, Ford, Anthony M, Potter, Nicola E, Greaves, Mel
I publikationen Leukemia (2018)

Multivalent small molecule pan-RAS inhibitors

av Welsch, Matthew E., Kaplan, Anna, Chambers, Jennifer M., Stokes, Michael E., Bos, Pieter H., Zask, Arie, Zhang, Yan, Sanchez-Martin, Marta, Badgley, Michael A., Huang, Christine S., Tran, Timothy H., Akkiraju, Hemanth, Brown, Lewis M., Nandakumar, Renu, Cremers, Serge, Yang, Wan S., Tong, Liang, Olive, Kenneth P., Ferrando, Adolfo, Stockwell, Brent R.
I publikationen Cell (2017)

Clonal evolution mechanisms in NT5C2 mutant relapsed acute lymphoblastic leukemia

av Tzoneva, Gannie, Dieck, Chelsea L., Oshima, Koichi, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Madubata, Chioma J., Khiabanian, Hossein, Yu, Jiangyan, Waanders, Esme, Iacobucci, Ilaria, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Loh, Mignon L., Kirschner-Schwabe, Renate, Mullighan, Charles G., Rabadan, Raul, Ferrando, Adolfo A.
I publikationen Nature (2018)

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

av Piovan, Erich, Yu, Jiyang, Tosello, Valeria, Herranz, Daniel, Ambesi-Impiombato, Alberto, Da Silva, Ana Carolina, Sanchez-Martin, Marta, Perez-Garcia, Arianne, Rigo, Isaura, Castillo, Mireia, Indraccolo, Stefano, Cross, Justin R, de Stanchina, Elisa, Paietta, Elisabeth, Racevskis, Janis, Rowe, Jacob M, Tallman, Martin S, Basso, Giuseppe, Meijerink, Jules P, Cordon-Cardo, Carlos, Califano, Andrea, Ferrando, Adolfo A.
Publicerad 2013

Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias

av Kucine, Nicole, Marubayashi, Sachie, Bhagwat, Neha, Papalexi, Efthymia, Koppikar, Priya, Sanchez Martin, Marta, Dong, Lauren, Tallman, Marty S., Paietta, Elisabeth, Wang, Kai, He, Jie, Lipson, Doron, Stephens, Phil, Miller, Vince, Rowe, Jacob M., Teruya-Feldstein, Julie, Mullighan, Charles G., Ferrando, Adolfo A., Krivtsov, Andrei, Armstrong, Scott, Leung, Laura, Ochiana, Stefan O., Chiosis, Gabriela, Levine, Ross L., Kleppe, Maria
I publikationen Blood (2015)

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

av Oshima, Koichi, Khiabanian, Hossein, da Silva-Almeida, Ana C., Tzoneva, Gannie, Abate, Francesco, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Carpenter, Zachary, Penson, Alex, Perez-Garcia, Arianne, Eckert, Cornelia, Nicolas, Concepción, Balbin, Milagros, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo A.
I publikationen Proc Natl Acad Sci U S A (2016)

Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias

av Wang, Kai, Sanchez-Martin, Marta, Wang, Xujun, Knapp, Kristina M., Koche, Richard, Vu, Ly, Nahas, Michelle K., He, Jie, Hadler, Michael, Stein, Eytan M, Tallman, Martin S., Donahue, Amy L, Frampton, Garrett M, Lipson, Doron, Roels, Steven, Stephens, Philip J., Sanford, Eric M, Brennan, Tim, Otto, Geoff A., Yelensky, Roman, Miller, Vincent A., Kharas, Michael G., Levine, Ross L., Ferrando, Adolfo, Armstrong, Scott A., Krivtsov, Andrei V.
I publikationen Leukemia (2016)