Family-based genetic risk prediction of multifactorial disease

Por Ruderfer, Douglas M, Korn, Joshua, Purcell, Shaun M
Publicado em 2010

Comprehensive polymorphism survey elucidates population structure of S. cerevisiae

Por Schacherer, Joseph, Shapiro, Joshua A., Ruderfer, Douglas M., Kruglyak, Leonid
Publicado em 2009

Genome-Wide Analysis of Nucleotide-Level Variation in Commonly Used Saccharomyces cerevisiae Strains

Por Schacherer, Joseph, Ruderfer, Douglas M., Gresham, David, Dolinski, Kara, Botstein, David, Kruglyak, Leonid
Publicado em 2007

Using Expression and Genotype to Predict Drug Response in Yeast

Por Ruderfer, Douglas M., Roberts, David C., Schreiber, Stuart L., Perlstein, Ethan O., Kruglyak, Leonid
Publicado em 2009

Telomere Length as a Quantitative Trait: Genome-Wide Survey and Genetic Mapping of Telomere Length-Control Genes in Yeast

Por Gatbonton, Tonibelle, Imbesi, Maria, Nelson, Melisa, Akey, Joshua M, Ruderfer, Douglas M, Kruglyak, Leonid, Simon, Julian A, Bedalov, Antonio
Publicado em 2006

Correction: Telomere Length as a Quantitative Trait: Genome-Wide Survey and Genetic Mapping of Telomere Length-Control Genes in Yeast

Por Gatbonton, Tonibelle, Imbesi, Maria, Nelson, Melisa, Akey, Joshua M, Ruderfer, Douglas M, Kruglyak, Leonid, Simon, Julian A, Bedalov, Antonio
Publicado em 2006

A family-based study of common polygenic variation and risk of schizophrenia

Por Ruderfer, Douglas M, Kirov, George, Chambert, Kimberly, Moran, Jennifer L, Owen, Michael J, O’Donovan, Michael C, Sklar, Pamela, Purcell, Shaun M
Publicado em 2011

No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia

Por Ruderfer, Douglas M, Lim, Elaine T, Genovese, Giulio, Moran, Jennifer L, Hultman, Christina M, Sullivan, Patrick F, McCarroll, Steven A, Holmans, Peter, Sklar, Pamela, Purcell, Shaun M
Publicado no Eur J Hum Genet (2015)

Patterns of genic intolerance of rare copy number variation in 59,898 human exomes

Por Ruderfer, Douglas M., Hamamsy, Tymor, Lek, Monkol, Karczewski, Konrad J., Kavanagh, David, Samocha, Kaitlin E., Daly, Mark J., MacArthur, Daniel G., Fromer, Menachem, Purcell, Shaun M.
Publicado no Nat Genet (2016)

Genetic modifiers and subtypes in schizophrenia: Investigations of age at onset, severity, sex and family history

Por Bergen, Sarah E., O’Dushlaine, Colm T., Lee, Phil H., Fanous, Ayman H., Ruderfer, Douglas M., Ripke, Stephan, Sullivan, Patrick F., Smoller, Jordan W., Purcell, Shaun M., Corvin, Aiden
Publicado no Schizophr Res (2014)

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

Por Genovese, Giulio, Fromer, Menachem, Stahl, Eli A., Ruderfer, Douglas M., Chambert, Kimberly, Landén, Mikael, Moran, Jennifer L., Purcell, Shaun M., Sklar, Pamela, Sullivan, Patrick F., Hultman, Christina M., McCarroll, Steven A.
Publicado no Nat Neurosci (2016)

The ExAC browser: displaying reference data information from over 60 000 exomes

Por Karczewski, Konrad J., Weisburd, Ben, Thomas, Brett, Solomonson, Matthew, Ruderfer, Douglas M., Kavanagh, David, Hamamsy, Tymor, Lek, Monkol, Samocha, Kaitlin E., Cummings, Beryl B., Birnbaum, Daniel, Daly, Mark J., MacArthur, Daniel G.
Publicado no Nucleic Acids Res (2017)

Rare Copy Number Variation in Treatment-Resistant Major Depressive Disorder

Por O’Dushlaine, Colm, Ripke, Stephan, Ruderfer, Douglas M., Hamilton, Steven P., Fava, Maurizio, Iosifescu, Dan V., Kohane, Isaac S., Churchill, Susanne E., Castro, Victor M., Clements, Caitlin C., Blumenthal, Sarah R., Murphy, Shawn N., Smoller, Jordan W., Perlis, Roy H.
Publicado em 2014

Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach

Por Ruderfer, Douglas M, Charney, Alexander W, Readhead, Ben, Kidd, Brian A, Kähler, Anna K, Kenny, Paul J, Keiser, Michael J, Moran, Jennifer L, Hultman, Christina M, Scott, Stuart A, Sullivan, Patrick F, Purcell, Shaun M, Dudley, Joel T, Sklar, Pamela
Publicado no Lancet Psychiatry (2016)

Discovery and Statistical Genotyping of Copy-Number Variation from Whole-Exome Sequencing Depth

Por Fromer, Menachem, Moran, Jennifer L., Chambert, Kimberly, Banks, Eric, Bergen, Sarah E., Ruderfer, Douglas M., Handsaker, Robert E., McCarroll, Steven A., O’Donovan, Michael C., Owen, Michael J., Kirov, George, Sullivan, Patrick F., Hultman, Christina M., Sklar, Pamela, Purcell, Shaun M.
Publicado em 2012

Mosaic copy number variation in schizophrenia

Por Ruderfer, Douglas M, Chambert, Kim, Moran, Jennifer, Talkowski, Michael, Chen, Elizabeth S, Gigek, Carolina, Gusella, James F, Blackwood, Douglas H, Corvin, Aiden, Gurling, Hugh M, Hultman, Christina M, Kirov, George, Magnusson, Patrick, O'Donovan, Michael C, Owen, Michael J, Pato, Carlos, St Clair, David, Sullivan, Patrick F, Purcell, Shaun M, Sklar, Pamela, Ernst, Carl
Publicado em 2013

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia

Por Ruderfer, Douglas M., Fanous, Ayman H., Ripke, Stephan, McQuillin, Andrew, Amdur, Richard L., Gejman, Pablo V., O’Donovan, Michael C., Andreassen, Ole A., Djurovic, Srdjan, Hultman, Christina M., Kelsoe, John R., Jamain, Stephane, Landén, Mikael, Leboyer, Marion, Nimgaonkar, Vishwajit, Nurnberger, John, Smoller, Jordan W., Craddock, Nick, Corvin, Aiden, Sullivan, Patrick F., Holmans, Peter, Sklar, Pamela, Kendler, Kenneth S.
Publicado em 2013

Dysregulation of miRNA-9 in a subset of schizophrenia patient-derived neural progenitor cells

Por Topol, Aaron, Zhu, Shijia, Hartley, Brigham J., English, Jane, Hauberg, Mads E., Readhead, Ben, Tran, Ngoc, Rittenhouse, Chelsea Ann, Simone, Anthony, Ruderfer, Douglas M., Johnson, Jessica, Hadas, Yoav, Gochman, Peter A., Wang, Ying-Chih, Shah, Hardik, Cagney, Gerard, Rapoport, Judith, Gage, Fred H., Dudley, Joel T., Sklar, Pamela, Mattheisen, Manuel, Cotter, David, Fang, Gang, Brennand, Kristen J.
Publicado no Cell Rep (2016)

A role for non-coding variation in schizophrenia

Por Roussos, Panos, Mitchell, Amanda C., Voloudakis, Georgios, Fullard, John F., Pothula, Venu M., Tsang, Jonathan, Stahl, Eli A., Georgakopoulos, Anastasios, Ruderfer, Douglas M., Charney, Alexander, Okada, Yukinori, Siminovitch, Katherine A., Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Plenge, Robert M., Raychaudhuri, Soumya, Fromer, Menachem, Purcell, Shaun M., Brennand, Kristen J., Robakis, Nikolaos K., Schadt, Eric E., Akbarian, Schahram, Sklar, Pamela
Publicado no Cell Rep (2014)

De novo mutations in schizophrenia implicate synaptic networks

Por Fromer, Menachem, Pocklington, Andrew J., Kavanagh, David H., Williams, Hywel J., Dwyer, Sarah, Gormley, Padhraig, Georgieva, Lyudmila, Rees, Elliott, Palta, Priit, Ruderfer, Douglas M., Carrera, Noa, Humphreys, Isla, Johnson, Jessica S., Roussos, Panos, Barker, Douglas D., Banks, Eric, Milanova, Vihra, Grant, Seth G., Hannon, Eilis, Rose, Samuel A., Chambert, Kimberly, Mahajan, Milind, Scolnick, Edward M., Moran, Jennifer L., Kirov, George, Palotie, Aarno, McCarroll, Steven A., Holmans, Peter, Sklar, Pamela, Owen, Michael J., Purcell, Shaun M., O’Donovan, Michael C.
Publicado no Nature (2014)