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Family-based genetic risk prediction of multifactorial disease

Genome-wide association studies have detected dozens of variants underlying complex diseases, although it is uncertain how often these discoveries will translate into clinically useful predictors. Here, to improve genetic risk prediction, we consider including phenotypic and genotypic information fr...

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Detalhes bibliográficos
Main Authors: Ruderfer, Douglas M, Korn, Joshua, Purcell, Shaun M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829927/
https://ncbi.nlm.nih.gov/pubmed/20193047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm123
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