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Family-based genetic risk prediction of multifactorial disease

Genome-wide association studies have detected dozens of variants underlying complex diseases, although it is uncertain how often these discoveries will translate into clinically useful predictors. Here, to improve genetic risk prediction, we consider including phenotypic and genotypic information fr...

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Bibliografiske detaljer
Main Authors: Ruderfer, Douglas M, Korn, Joshua, Purcell, Shaun M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829927/
https://ncbi.nlm.nih.gov/pubmed/20193047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm123
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