Expanding cultural and ancestral representation in psychiatric genetic studies

por Kang, Jooeun, Ruderfer, Douglas M.
Publicado no Neuropsychopharmacology (2020)

Family-based genetic risk prediction of multifactorial disease

por Ruderfer, Douglas M, Korn, Joshua, Purcell, Shaun M
Publicado em 2010

Comprehensive polymorphism survey elucidates population structure of S. cerevisiae

por Schacherer, Joseph, Shapiro, Joshua A., Ruderfer, Douglas M., Kruglyak, Leonid
Publicado em 2009

Genome-Wide Analysis of Nucleotide-Level Variation in Commonly Used Saccharomyces cerevisiae Strains

por Schacherer, Joseph, Ruderfer, Douglas M., Gresham, David, Dolinski, Kara, Botstein, David, Kruglyak, Leonid
Publicado em 2007

Learning Opportunities for Drug Repositioning via GWAS and PheWAS Findings

por Yin, Wen, Gao, Cheng, Xu, Yaomin, Li, Bingshan, Ruderfer, Douglas M., Chen, You
Publicado no AMIA Jt Summits Transl Sci Proc (2018)

Using Expression and Genotype to Predict Drug Response in Yeast

por Ruderfer, Douglas M., Roberts, David C., Schreiber, Stuart L., Perlstein, Ethan O., Kruglyak, Leonid
Publicado em 2009

Telomere Length as a Quantitative Trait: Genome-Wide Survey and Genetic Mapping of Telomere Length-Control Genes in Yeast

por Gatbonton, Tonibelle, Imbesi, Maria, Nelson, Melisa, Akey, Joshua M, Ruderfer, Douglas M, Kruglyak, Leonid, Simon, Julian A, Bedalov, Antonio
Publicado em 2006

Correction: Telomere Length as a Quantitative Trait: Genome-Wide Survey and Genetic Mapping of Telomere Length-Control Genes in Yeast

por Gatbonton, Tonibelle, Imbesi, Maria, Nelson, Melisa, Akey, Joshua M, Ruderfer, Douglas M, Kruglyak, Leonid, Simon, Julian A, Bedalov, Antonio
Publicado em 2006

Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide

por Ruderfer, Douglas M., Walsh, Colin G., Aguirre, Matthew W., Tanigawa, Yosuke, Ribeiro, Jessica D., Franklin, Joseph C., Rivas, Manuel A.
Publicado no Mol Psychiatry (2019)

A family-based study of common polygenic variation and risk of schizophrenia

por Ruderfer, Douglas M, Kirov, George, Chambert, Kimberly, Moran, Jennifer L, Owen, Michael J, O’Donovan, Michael C, Sklar, Pamela, Purcell, Shaun M
Publicado em 2011

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains

por Hoffman, Gabriel E., Hartley, Brigham J., Flaherty, Erin, Ladran, Ian, Gochman, Peter, Ruderfer, Douglas M., Stahl, Eli A., Rapoport, Judith, Sklar, Pamela, Brennand, Kristen J.
Publicado no Nat Commun (2017)

No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia

por Ruderfer, Douglas M, Lim, Elaine T, Genovese, Giulio, Moran, Jennifer L, Hultman, Christina M, Sullivan, Patrick F, McCarroll, Steven A, Holmans, Peter, Sklar, Pamela, Purcell, Shaun M
Publicado no Eur J Hum Genet (2015)

Patterns of genic intolerance of rare copy number variation in 59,898 human exomes

por Ruderfer, Douglas M., Hamamsy, Tymor, Lek, Monkol, Karczewski, Konrad J., Kavanagh, David, Samocha, Kaitlin E., Daly, Mark J., MacArthur, Daniel G., Fromer, Menachem, Purcell, Shaun M.
Publicado no Nat Genet (2016)

Genetic modifiers and subtypes in schizophrenia: Investigations of age at onset, severity, sex and family history

por Bergen, Sarah E., O’Dushlaine, Colm T., Lee, Phil H., Fanous, Ayman H., Ruderfer, Douglas M., Ripke, Stephan, Sullivan, Patrick F., Smoller, Jordan W., Purcell, Shaun M., Corvin, Aiden
Publicado no Schizophr Res (2014)

Improving genetic prediction by leveraging genetic correlations among human diseases and traits

por Maier, Robert M., Zhu, Zhihong, Lee, Sang Hong, Trzaskowski, Maciej, Ruderfer, Douglas M., Stahl, Eli A., Ripke, Stephan, Wray, Naomi R., Yang, Jian, Visscher, Peter M., Robinson, Matthew R.
Publicado no Nat Commun (2018)

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

por Genovese, Giulio, Fromer, Menachem, Stahl, Eli A., Ruderfer, Douglas M., Chambert, Kimberly, Landén, Mikael, Moran, Jennifer L., Purcell, Shaun M., Sklar, Pamela, Sullivan, Patrick F., Hultman, Christina M., McCarroll, Steven A.
Publicado no Nat Neurosci (2016)

The ExAC browser: displaying reference data information from over 60 000 exomes

por Karczewski, Konrad J., Weisburd, Ben, Thomas, Brett, Solomonson, Matthew, Ruderfer, Douglas M., Kavanagh, David, Hamamsy, Tymor, Lek, Monkol, Samocha, Kaitlin E., Cummings, Beryl B., Birnbaum, Daniel, Daly, Mark J., MacArthur, Daniel G.
Publicado no Nucleic Acids Res (2017)

APOE ε4-specific Associations of VEGF Gene Family Expression with Cognitive Aging and Alzheimer’s Disease

por Moore, Annah M., Mahoney, Emily, Dumitrescu, Logan, De Jager, Philip L., Koran, Mary Ellen I., Petyuk, Vladislav A., Robinson, Renã AS, Ruderfer, Douglas M., Cox, Nancy J., Schneider, Julie A., Bennett, David A., Jefferson, Angela L., Hohman, Timothy J.
Publicado no Neurobiol Aging (2019)

Rare Copy Number Variation in Treatment-Resistant Major Depressive Disorder

por O’Dushlaine, Colm, Ripke, Stephan, Ruderfer, Douglas M., Hamilton, Steven P., Fava, Maurizio, Iosifescu, Dan V., Kohane, Isaac S., Churchill, Susanne E., Castro, Victor M., Clements, Caitlin C., Blumenthal, Sarah R., Murphy, Shawn N., Smoller, Jordan W., Perlis, Roy H.
Publicado em 2014

Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach

por Ruderfer, Douglas M, Charney, Alexander W, Readhead, Ben, Kidd, Brian A, Kähler, Anna K, Kenny, Paul J, Keiser, Michael J, Moran, Jennifer L, Hultman, Christina M, Scott, Stuart A, Sullivan, Patrick F, Purcell, Shaun M, Dudley, Joel T, Sklar, Pamela
Publicado no Lancet Psychiatry (2016)