Using Expression and Genotype to Predict Drug Response in Yeast

Personalized, or genomic, medicine entails tailoring pharmacological therapies according to individual genetic variation at genomic loci encoding proteins in drug-response pathways. It has been previously shown that steady-state mRNA expression can be used to predict the drug response (i.e., sensiti...

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Bibliographic Details
Main Authors: Ruderfer, Douglas M., Roberts, David C., Schreiber, Stuart L., Perlstein, Ethan O., Kruglyak, Leonid
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731853/
https://ncbi.nlm.nih.gov/pubmed/19730698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006907
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