No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia

Recessive inheritance of gene disrupting alleles, either through homozygosity at a specific site or compound heterozygosity, have been demonstrated to underlie many Mendelian diseases and some complex psychiatric disorders. On the basis of exome sequencing data, an increased burden of complete knock...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Eur J Hum Genet
Huvudupphovsmän: Ruderfer, Douglas M, Lim, Elaine T, Genovese, Giulio, Moran, Jennifer L, Hultman, Christina M, Sullivan, Patrick F, McCarroll, Steven A, Holmans, Peter, Sklar, Pamela, Purcell, Shaun M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Short Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666583/
https://ncbi.nlm.nih.gov/pubmed/25370044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.228
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk