No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia

Recessive inheritance of gene disrupting alleles, either through homozygosity at a specific site or compound heterozygosity, have been demonstrated to underlie many Mendelian diseases and some complex psychiatric disorders. On the basis of exome sequencing data, an increased burden of complete knock...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Hum Genet
Prif Awduron: Ruderfer, Douglas M, Lim, Elaine T, Genovese, Giulio, Moran, Jennifer L, Hultman, Christina M, Sullivan, Patrick F, McCarroll, Steven A, Holmans, Peter, Sklar, Pamela, Purcell, Shaun M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Short Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666583/
https://ncbi.nlm.nih.gov/pubmed/25370044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.228
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