Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors

par Wu, Xiongyu, Öhrngren, Per, Joshi, Advait A., Trejos, Alejandro, Persson, Magnus, Arvela, Riina K., Wallberg, Hans, Vrang, Lotta, Rosenquist, Åsa, Samuelsson, Bertil B., Unge, Johan, Larhed, Mats
Publié 2012

In Vitro Activity and Preclinical Profile of TMC435350, a Potent Hepatitis C Virus Protease Inhibitor

par Lin, Tse-I, Lenz, Oliver, Fanning, Gregory, Verbinnen, Thierry, Delouvroy, Frédéric, Scholliers, Annick, Vermeiren, Katrien, Rosenquist, Åsa, Edlund, Michael, Samuelsson, Bertil, Vrang, Lotta, de Kock, Herman, Wigerinck, Piet, Raboisson, Pierre, Simmen, Kenneth
Publié 2009

Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses

par Tampere, Marianna, Pettke, Aleksandra, Salata, Cristiano, Wallner, Olov, Koolmeister, Tobias, Cazares-Körner, Armando, Visnes, Torkild, Hesselman, Maria Carmen, Kunold, Elena, Wiita, Elisee, Kalderén, Christina, Lightowler, Molly, Jemth, Ann-Sofie, Lehtiö, Janne, Rosenquist, Åsa, Warpman-Berglund, Ulrika, Helleday, Thomas, Mirazimi, Ali, Jafari, Rozbeh, Puumalainen, Marjo-Riitta
Publié dans Viruses (2020)

Antiviral Activity and Mode of Action of TMC647078, a Novel Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase

par Berke, Jan Martin, Vijgen, Leen, Lachau-Durand, Sophie, Powdrill, Megan H., Rawe, Svea, Sjuvarsson, Elena, Eriksson, Staffan, Götte, Matthias, Fransen, Els, Dehertogh, Pascale, Van den Eynde, Christel, Leclercq, Laurent, Jonckers, Tim H. M., Raboisson, Pierre, Nilsson, Magnus, Samuelsson, Bertil, Rosenquist, Åsa, Fanning, Gregory C., Lin, Tse-I
Publié 2011