Points: Clinical Algorithms: Compulsory detention in hospital under the Mental Health Act 1983

Autor Rhode, Peter
Vydáno 1987

The IL-15-based superagonist ALT-803 promotes the antigen-independent conversion of memory CD8(+) T cells into innate-like effector cells with antitumor activity

Autor Wong, Hing C, Jeng, Emily K, Rhode, Peter R
Vydáno 2013

Enhanced efficacy of IL-15-based ALT-803 superagonist complex in combination with immune checkpoint inhibitors in hematologic and metastatic mouse tumor models

Autor Xu, Wenxin, Marcus, Warren D, Rhode, Peter R, Wong, Hing C
Vydáno v J Immunother Cancer (2014)

Evaluation of a novel CD20-targeted IL-15 immunotherapeutic with potent activity against B cell lymphoma

Autor Liu, Bai, Kong, Lin, Marcus, Warren D, Chen, Xiaoyue, Han, Kaiping, Rhode, Peter R, Wong, Hing C
Vydáno v J Immunother Cancer (2014)

CITN-06: a Phase I/expansion trial of alt-803, an IL-15 superagonist, in patients with advanced melanoma

Autor Margolin, Kim, Wong, Hing C, Morishima, Chihiro, Hernandez, Liza, Ernstoff, Marc, Rhode, Peter R, Waldmann, Thomas A
Vydáno v J Immunother Cancer (2014)

Enhanced efficacy of ALT-803, an IL-15-based superagonist complex, in combination with immune checkpoint inhibitors in an orthotopic muscle invasive bladder tumor model in mice

Autor Xu, Wenxin, Kage, Karen, Marcus, Warren D, Newman, Robby, Alter, Sarah, Rhode, Peter R, Wong, Hing C
Vydáno v J Immunother Cancer (2015)

A phase I study evaluating the pharmacokinetics, safety and tolerability of an antibody-based tissue factor antagonist in subjects with acute lung injury or acute respiratory distr...

Autor Morris, Peter E, Steingrub, Jay S, Huang, Bee Y, Tang, Shamay, Liu, Patrick M, Rhode, Peter R, Wong, Hing C
Vydáno 2012

The IL-15 superagonist ALT-803 enhances anti-CD20 antibody-directed NK cell ADCC and in vivo clearance of B cell lymphomas

Autor Rosario, Maximillian, Liu, Bai, Kong, Lin, Schneider, Stephanie E, Jeng, Emily K, Rhode, Peter R, Wong, Hing C, Fehniger, Todd A
Vydáno v J Immunother Cancer (2014)

Effectiveness of two different dose administration regimens of an IL-15 superagonist complex (ALT-803) in an orthotopic bladder cancer mouse model

Autor Furuya, Hideki, Chan, Owen T. M., Pagano, Ian, Zhu, Chengjun, Kim, Nari, Peres, Rafael, Hokutan, Kanani, Alter, Sarah, Rhode, Peter, Rosser, Charles J.
Vydáno v J Transl Med (2019)

Combination therapy of an IL-15 superagonist complex, ALT-803, and a tumor targeting monoclonal antibody promotes direct antitumor activity and protective vaccinal effect in a syng...

Autor Chen, Xiaoyue, Liu, Bai, Han, Kaiping, Kong, Lin, Noel, Terra, Jeng, Emily K, Alter, Sarah, Rubinstein, Mark, Rhode, Peter R, Wong, Hing C
Vydáno v J Immunother Cancer (2015)

Novel Human Interleukin-15 Agonists

Autor Zhu, Xiaoyun, Marcus, Warren D., Xu, Wenxin, Lee, Hyung-Il, Han, Kaiping, Egan, Jack O., Yovandich, Jason L., Rhode, Peter R., Wong, Hing C.
Vydáno 2009

Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model

Autor Mathios, Dimitrios, Park, Chul-Kee, Marcus, Warren D., Alter, Sarah, Rhode, Peter R., Jeng, Emily K., Wong, Hing C., Pardoll, Drew M., Lim, Michael
Vydáno v Int J Cancer (2015)

Evaluation of the biological activities of the IL-15 superagonist complex, ALT-803, following intravenous versus subcutaneous administration in murine models

Autor Liu, Bai, Jones, Monica, Kong, Lin, Noel, Terra, Jeng, Emily K., Shi, Sixiang, England, Christopher G., Alter, Sarah, Miller, Jeffrey S., Cai, Weibo, Rhode, Peter R., Wong, Hing C.
Vydáno v Cytokine (2018)

Novel antitumor mechanism-of-action of an IL-2 fusion protein mediated by tumor associated macrophage repolarization and innate-like CD8+ memory T cells

Autor Xu, Wenxin, Egan, Jack O, Liu, Bai, Chen, Xiaoyue, You, Lijing, Han, Kaiping, Marcus, Warren D, Kong, Lin, Jones, Monica, Jeng, Emily K, Rhode, Peter R, Wong, Hing C
Vydáno v J Immunother Cancer (2014)

Interleukin-15:Interleukin-15 receptor α scaffold for creation of multivalent targeted immune molecules

Autor Wong, Richard L., Liu, Bai, Zhu, Xiaoyun, You, Lijing, Kong, Lin, Han, Kai-Ping, Lee, Hyung-il, Chavaillaz, Pierre-Andre, Jin, Moonsoo, Wang, Yi, Rhode, Peter R., Wong, Hing C.
Vydáno 2011

Phase 1 trial of ALT-801, an interleukin-2/T cell receptor fusion protein targeting p53 (aa264-272)/HLA-A*0201 complex, in patients with advanced malignancies

Autor Fishman, Mayer N., Thompson, John A., Pennock, Gregory K., Gonzalez, Rene, Diez, Luz M., Daud, Adil I., Weber, Jeffery S., Huang, Bee Y., Tang, Shamay, Rhode, Peter R., Wong, Hing C.
Vydáno 2011

Intravesical ALT-803 and BCG Treatment Reduces Tumor Burden in a Carcinogen Induced Bladder Cancer Rat Model; a Role for Cytokine Production and NK Cell Expansion

Autor Gomes-Giacoia, Evan, Miyake, Makito, Goodison, Steve, Sriharan, Aravindhan, Zhang, Ge, You, Lijing, Egan, Jack O., Rhode, Peter R., Parker, Alexander S., Chai, Karl X., Wong, Hing C., Rosser, Charles J.
Vydáno 2014

IL-15:IL-15 receptor alpha superagonist complex: High-level co-expression in recombinant mammalian cells, purification and characterization

Autor Han, Kai-ping, Zhu, Xiaoyun, Liu, Bai, Jeng, Emily, Kong, Lin, Yovandich, Jason L., Vyas, Vinay V., Marcus, Warren D., Chavaillaz, Pierre-Andre, Romero, Christian A., Rhode, Peter R., Wong, Hing C.
Vydáno 2011

Efficacy and Mechanism-of-Action of a Novel Superagonist Interleukin-15: Interleukin-15 Receptor α/Fc Fusion Complex in Syngeneic Murine Models of Multiple Myeloma

Autor Xu, Wenxin, Jones, Monica, Liu, Bai, Zhu, Xiaoyun, Johnson, C. Bryce, Edwards, Ana C., Kong, Lin, Jeng, Emily K., Han, Kaiping, Marcus, Warren D., Rubinstein, Mark P., Rhode, Peter R., Wong, Hing C.
Vydáno 2013

A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses

Autor Liu, Bai, Kong, Lin, Han, Kaiping, Hong, Hao, Marcus, Warren D., Chen, Xiaoyue, Jeng, Emily K., Alter, Sarah, Zhu, Xiaoyun, Rubinstein, Mark P., Shi, Sixiang, Rhode, Peter R., Cai, Weibo, Wong, Hing C.
Vydáno v J Biol Chem (2016)