Why is immunotherapy for glioblastoma “Lag”-ging

著者: Mathios, Dimitrios, Lim, Michael
出版年 Oncotarget (2019)

New Prospects for Molecular Targets for Chordomas

著者: Ozair, Mohammad Zeeshan, Shah, Pavan, Mathios, Dimitrios, Lim, Michael, Moss, Nelson S.
出版年 Neurosurg Clin N Am (2020)

Reduced CSF leak in complete calvarial reconstructions of microvascular decompression craniectomies using calcium phosphate cement

著者: Eseonu, Chikezie I., Goodwin, C. Rory, Zhou, Xin, Theodros, Debebe, Bender, Matthew T., Mathios, Dimitrios, Bettegowda, Chetan, Lim, Michael
出版年 J Neurosurg (2015)

IT-21 PD-1 BLOCKADE SHOWS SYNERGISTIC SURVIVAL, ANTI-TUMOR IMMUNE RESPONSE AND LONG-TERM MEMORY WITH INTERSTITIAL BUT NOT SYSTEMIC CHEMOTHERAPY: STUDY IN A MURINE GLIOBLASTOMA MODE...

著者: Mathios, Dimitrios, Phallen, Jillian, Park, Chul-Kee, Jackson, Christopher, Nicholas, Sarah, Tyler, Betty, Pardoll, Drew, Brem, Henry, Lim, Michael
出版事項 2014

Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model

著者: Mathios, Dimitrios, Park, Chul-Kee, Marcus, Warren D., Alter, Sarah, Rhode, Peter R., Jeng, Emily K., Wong, Hing C., Pardoll, Drew M., Lim, Michael
出版年 Int J Cancer (2015)

PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment

著者: Mathios, Dimitrios, Ruzevick, Jacob, Jackson, Christopher M., Xu, Haiying, Shah, Sagar, Taube, Janis M., Burger, Peter C., McCarthy, Edward F., Quinones-Hinojosa, Alfredo, Pardoll, Drew M., Lim, Michael
出版年 J Neurooncol (2014)

Optimizing the delivery of chemotherapy in the setting of immunotherapy in a preclinical glioblastoma model

著者: Mathios, Dimitrios, Kim, Jennifer, Phallen, Jillian, Mangraviti, Antonella, Park, Chul-Kee, Theodros, Debebe, Jackson, Christopher, Garzon-Muvdi, Tomas, Kim, Eileen, Ye, Xiaobu, Tyler, Betty, Brem, Henry, Pardoll, Drew, Lim, Michael
出版年 J Immunother Cancer (2015)

Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma

著者: Hwang, Taeyoung, Mathios, Dimitrios, McDonald, Kerrie L., Daris, Irene, Park, Sung-Hye, Burger, Peter C., Kim, Sojin, Dho, Yun-Sik, Carolyn, Hruban, Bettegowda, Chetan, Shin, Joo Heon, Lim, Michael, Park, Chul-Kee
出版年 Acta Neuropathol Commun (2019)

Low-dose oncolytic adenovirus therapy overcomes tumor-induced immune suppression and sensitizes intracranial gliomas to anti-PD-1 therapy

著者: Belcaid, Zineb, Berrevoets, Cor, Choi, John, van Beelen, Edward, Stavrakaki, Eftychia, Pierson, Tessa, Kloezeman, Jenneke, Routkevitch, Denis, van der Kaaij, Mariëlle, van der Ploeg, Alicia, Mathios, Dimitrios, Sleijfer, Stefan, Dirven, Clemens, Lim, Michael, Debets, Reno, Lamfers, Martine L M
出版年 Neurooncol Adv (2020)

IMPS-20 COMBINATION THERAPY WITH ANTI-PD-1, ANTI-TIM-3, AND FOCAL RADIATION RESULTS IN REGRESSION OF MURINE GLIOMAS

著者: Kim, Jennifer E., Patel, Mira A., Mangraviti, Antonella, Polanczyk, Magda, Kim, Eileen S., Theodros, Debebe, Velarde, Esteban, Liu, Ann, Sankey, Eric, Mathios, Dimitrios, Jackson, Christopher M., Olivi, Alessandro, Tran, Phuoc, Drake, Charles G., Tyler, Betty, Ye, Xiaobu, Brem, Henry, Pardoll, Drew M., Lim, Michael
出版年 Neuro Oncol (2015)

Anti–PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM

著者: Mathios, Dimitrios, Kim, Jennifer E., Mangraviti, Antonella, Phallen, Jillian, Park, Chul-Kee, Jackson, Christopher M., Garzon-Muvdi, Tomas, Kim, Eileen, Theodros, Debebe, Polanczyk, Magdalena, Martin, Allison M., Suk, Ian, Ye, Xiaobu, Tyler, Betty, Bettegowda, Chetan, Brem, Henry, Pardoll, Drew M., Lim, Michael
出版年 Sci Transl Med (2016)

Focal Radiation Therapy Combined with 4-1BB Activation and CTLA-4 Blockade Yields Long-Term Survival and a Protective Antigen-Specific Memory Response in a Murine Glioma Model

著者: Belcaid, Zineb, Phallen, Jillian A., Zeng, Jing, See, Alfred P., Mathios, Dimitrios, Gottschalk, Chelsea, Nicholas, Sarah, Kellett, Meghan, Ruzevick, Jacob, Jackson, Christopher, Albesiano, Emilia, Durham, Nicholas M., Ye, Xiaobu, Tran, Phuoc T., Tyler, Betty, Wong, John W., Brem, Henry, Pardoll, Drew M., Drake, Charles G., Lim, Michael
出版事項 2014

Contrasting impact of corticosteroids on anti-PD-1 immunotherapy efficacy for tumor histologies located within or outside the central nervous system

著者: Maxwell, Russell, Luksik, Andrew S., Garzon-Muvdi, Tomas, Hung, Alice L., Kim, Eileen S., Wu, Adela, Xia, Yuanxuan, Belcaid, Zineb, Gorelick, Noah, Choi, John, Theodros, Debebe, Jackson, Christopher M., Mathios, Dimitrios, Ye, Xiaobu, Tran, Phuoc T., Redmond, Kristin J., Brem, Henry, Pardoll, Drew M., Kleinberg, Lawrence R., Lim, Michael
出版年 Oncoimmunology (2018)

Expression of LAG-3 and efficacy of combination treatment with anti-LAG-3 and anti-PD-1 monoclonal antibodies in glioblastoma

著者: Harris-Bookman, Sarah, Mathios, Dimitrios, Martin, Allison M., Xia, Yuanxuan, Kim, Eileen, Xu, Haiying, Belcaid, Zineb, Polanczyk, Magdalena, Barberi, Theresa, Theodros, Debebe, Kim, Jennifer, Taube, Janis M., Burger, Peter C., Selby, Mark, Taitt, Corina, Korman, Alan, Ye, Xiaobu, Drake, Charles G., Brem, Henry, Pardoll, Drew M., Lim, Michael
出版年 Int J Cancer (2018)

Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden

著者: Stone, Meredith L., Chiappinelli, Katherine B., Li, Huili, Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Mathios, Dimitrios, Lim, Michael, Shih, Ie-Ming, Wang, Tian-Li, Hung, Chien-Fu, Bhargava, Vipul, Wiehagen, Karla R., Cowley, Glenn S., Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Baylin, Stephen B., Zahnow, Cynthia A.
出版年 Proc Natl Acad Sci U S A (2017)

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM

著者: Hung, Alice L., Maxwell, Russell, Theodros, Debebe, Belcaid, Zineb, Mathios, Dimitrios, Luksik, Andrew S., Kim, Eileen, Wu, Adela, Xia, Yuanxuan, Garzon-Muvdi, Tomas, Jackson, Christopher, Ye, Xiaobu, Tyler, Betty, Selby, Mark, Korman, Alan, Barnhart, Bryan, Park, Su-Myeong, Youn, Je-In, Chowdhury, Tamrin, Park, Chul-Kee, Brem, Henry, Pardoll, Drew M., Lim, Michael
出版年 Oncoimmunology (2018)

Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic

著者: Stone, Meredith L., Chiappinelli, Katherine B., Li, Huili, Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Mathios, Dimitrios, Lim, Michael, Shih, Ie-Ming, Wang, Tian-Li, Hung, Chien-Fu, Bhargava, Vipul, Wiehagen, Karla R., Cowley, Glenn S., Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Baylin, Stephen B., Zahnow, Cynthia A.
出版年 Proc Natl Acad Sci U S A (2018)

Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

著者: Patel, Mira A., Kim, Jennifer E., Theodros, Debebe, Tam, Ada, Velarde, Esteban, Kochel, Christina M., Francica, Brian, Nirschl, Thomas R., Ghasemzadeh, Ali, Mathios, Dimitrios, Harris-Bookman, Sarah, Jackson, Christopher C., Jackson, Christina, Ye, Xiaobu, Tran, Phuoc T., Tyler, Betty, Coric, Vladimir, Selby, Mark, Brem, Henry, Drake, Charles G., Pardoll, Drew M., Lim, Michael
出版年 J Immunother Cancer (2016)

Erratum to: Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

著者: Patel, Mira A., Kim, Jennifer E., Theodros, Debebe, Tam, Ada, Velarde, Esteban, Kochel, Christina M., Francica, Brian, Nirschl, Thomas R., Ghasemzadeh, Ali, Mathios, Dimitrios, Harris-Bookman, Sarah, Jackson, Christopher C., Jackson, Christina, Ye, Xiaobu, Tran, Phuoc T., Tyler, Betty, Coric, Vladimir, Selby, Mark, Brem, Henry, Drake, Charles G., Pardoll, Drew M., Lim, Michael
出版年 J Immunother Cancer (2016)

Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas

著者: Kim, Jennifer E., Patel, Mira A., Mangraviti, Antonella, Kim, Eileen S., Theodros, Debebe, Velarde, Esteban, Liu, Ann, Sankey, Eric W., Tam, Ada, Xu, Haiying, Mathios, Dimitrios, Jackson, Christopher M., Harris-Bookman, Sarah, Garzon-Muvdi, Tomas, Sheu, Mary, Martin, Allison M., Tyler, Betty M., Tran, Phuoc T., Ye, Xiaobu, Olivi, Alessandro, Taube, Janis M., Burger, Peter C., Drake, Charles G., Brem, Henry, Pardoll, Drew M., Lim, Michael
出版年 Clin Cancer Res (2016)