Why is immunotherapy for glioblastoma “Lag”-ging

af Mathios, Dimitrios, Lim, Michael
Udgivet i Oncotarget (2019)

New Prospects for Molecular Targets for Chordomas

af Ozair, Mohammad Zeeshan, Shah, Pavan, Mathios, Dimitrios, Lim, Michael, Moss, Nelson S.
Udgivet i Neurosurg Clin N Am (2020)

Reduced CSF leak in complete calvarial reconstructions of microvascular decompression craniectomies using calcium phosphate cement

af Eseonu, Chikezie I., Goodwin, C. Rory, Zhou, Xin, Theodros, Debebe, Bender, Matthew T., Mathios, Dimitrios, Bettegowda, Chetan, Lim, Michael
Udgivet i J Neurosurg (2015)

IT-21 PD-1 BLOCKADE SHOWS SYNERGISTIC SURVIVAL, ANTI-TUMOR IMMUNE RESPONSE AND LONG-TERM MEMORY WITH INTERSTITIAL BUT NOT SYSTEMIC CHEMOTHERAPY: STUDY IN A MURINE GLIOBLASTOMA MODE...

af Mathios, Dimitrios, Phallen, Jillian, Park, Chul-Kee, Jackson, Christopher, Nicholas, Sarah, Tyler, Betty, Pardoll, Drew, Brem, Henry, Lim, Michael
Udgivet 2014

Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model

af Mathios, Dimitrios, Park, Chul-Kee, Marcus, Warren D., Alter, Sarah, Rhode, Peter R., Jeng, Emily K., Wong, Hing C., Pardoll, Drew M., Lim, Michael
Udgivet i Int J Cancer (2015)

PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment

af Mathios, Dimitrios, Ruzevick, Jacob, Jackson, Christopher M., Xu, Haiying, Shah, Sagar, Taube, Janis M., Burger, Peter C., McCarthy, Edward F., Quinones-Hinojosa, Alfredo, Pardoll, Drew M., Lim, Michael
Udgivet i J Neurooncol (2014)

Optimizing the delivery of chemotherapy in the setting of immunotherapy in a preclinical glioblastoma model

af Mathios, Dimitrios, Kim, Jennifer, Phallen, Jillian, Mangraviti, Antonella, Park, Chul-Kee, Theodros, Debebe, Jackson, Christopher, Garzon-Muvdi, Tomas, Kim, Eileen, Ye, Xiaobu, Tyler, Betty, Brem, Henry, Pardoll, Drew, Lim, Michael
Udgivet i J Immunother Cancer (2015)

Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma

af Hwang, Taeyoung, Mathios, Dimitrios, McDonald, Kerrie L., Daris, Irene, Park, Sung-Hye, Burger, Peter C., Kim, Sojin, Dho, Yun-Sik, Carolyn, Hruban, Bettegowda, Chetan, Shin, Joo Heon, Lim, Michael, Park, Chul-Kee
Udgivet i Acta Neuropathol Commun (2019)

Low-dose oncolytic adenovirus therapy overcomes tumor-induced immune suppression and sensitizes intracranial gliomas to anti-PD-1 therapy

af Belcaid, Zineb, Berrevoets, Cor, Choi, John, van Beelen, Edward, Stavrakaki, Eftychia, Pierson, Tessa, Kloezeman, Jenneke, Routkevitch, Denis, van der Kaaij, Mariëlle, van der Ploeg, Alicia, Mathios, Dimitrios, Sleijfer, Stefan, Dirven, Clemens, Lim, Michael, Debets, Reno, Lamfers, Martine L M
Udgivet i Neurooncol Adv (2020)

IMPS-20 COMBINATION THERAPY WITH ANTI-PD-1, ANTI-TIM-3, AND FOCAL RADIATION RESULTS IN REGRESSION OF MURINE GLIOMAS

af Kim, Jennifer E., Patel, Mira A., Mangraviti, Antonella, Polanczyk, Magda, Kim, Eileen S., Theodros, Debebe, Velarde, Esteban, Liu, Ann, Sankey, Eric, Mathios, Dimitrios, Jackson, Christopher M., Olivi, Alessandro, Tran, Phuoc, Drake, Charles G., Tyler, Betty, Ye, Xiaobu, Brem, Henry, Pardoll, Drew M., Lim, Michael
Udgivet i Neuro Oncol (2015)

Anti–PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM

af Mathios, Dimitrios, Kim, Jennifer E., Mangraviti, Antonella, Phallen, Jillian, Park, Chul-Kee, Jackson, Christopher M., Garzon-Muvdi, Tomas, Kim, Eileen, Theodros, Debebe, Polanczyk, Magdalena, Martin, Allison M., Suk, Ian, Ye, Xiaobu, Tyler, Betty, Bettegowda, Chetan, Brem, Henry, Pardoll, Drew M., Lim, Michael
Udgivet i Sci Transl Med (2016)

Focal Radiation Therapy Combined with 4-1BB Activation and CTLA-4 Blockade Yields Long-Term Survival and a Protective Antigen-Specific Memory Response in a Murine Glioma Model

af Belcaid, Zineb, Phallen, Jillian A., Zeng, Jing, See, Alfred P., Mathios, Dimitrios, Gottschalk, Chelsea, Nicholas, Sarah, Kellett, Meghan, Ruzevick, Jacob, Jackson, Christopher, Albesiano, Emilia, Durham, Nicholas M., Ye, Xiaobu, Tran, Phuoc T., Tyler, Betty, Wong, John W., Brem, Henry, Pardoll, Drew M., Drake, Charles G., Lim, Michael
Udgivet 2014

Contrasting impact of corticosteroids on anti-PD-1 immunotherapy efficacy for tumor histologies located within or outside the central nervous system

af Maxwell, Russell, Luksik, Andrew S., Garzon-Muvdi, Tomas, Hung, Alice L., Kim, Eileen S., Wu, Adela, Xia, Yuanxuan, Belcaid, Zineb, Gorelick, Noah, Choi, John, Theodros, Debebe, Jackson, Christopher M., Mathios, Dimitrios, Ye, Xiaobu, Tran, Phuoc T., Redmond, Kristin J., Brem, Henry, Pardoll, Drew M., Kleinberg, Lawrence R., Lim, Michael
Udgivet i Oncoimmunology (2018)

Expression of LAG-3 and efficacy of combination treatment with anti-LAG-3 and anti-PD-1 monoclonal antibodies in glioblastoma

af Harris-Bookman, Sarah, Mathios, Dimitrios, Martin, Allison M., Xia, Yuanxuan, Kim, Eileen, Xu, Haiying, Belcaid, Zineb, Polanczyk, Magdalena, Barberi, Theresa, Theodros, Debebe, Kim, Jennifer, Taube, Janis M., Burger, Peter C., Selby, Mark, Taitt, Corina, Korman, Alan, Ye, Xiaobu, Drake, Charles G., Brem, Henry, Pardoll, Drew M., Lim, Michael
Udgivet i Int J Cancer (2018)

Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden

af Stone, Meredith L., Chiappinelli, Katherine B., Li, Huili, Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Mathios, Dimitrios, Lim, Michael, Shih, Ie-Ming, Wang, Tian-Li, Hung, Chien-Fu, Bhargava, Vipul, Wiehagen, Karla R., Cowley, Glenn S., Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Baylin, Stephen B., Zahnow, Cynthia A.
Udgivet i Proc Natl Acad Sci U S A (2017)

TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM

af Hung, Alice L., Maxwell, Russell, Theodros, Debebe, Belcaid, Zineb, Mathios, Dimitrios, Luksik, Andrew S., Kim, Eileen, Wu, Adela, Xia, Yuanxuan, Garzon-Muvdi, Tomas, Jackson, Christopher, Ye, Xiaobu, Tyler, Betty, Selby, Mark, Korman, Alan, Barnhart, Bryan, Park, Su-Myeong, Youn, Je-In, Chowdhury, Tamrin, Park, Chul-Kee, Brem, Henry, Pardoll, Drew M., Lim, Michael
Udgivet i Oncoimmunology (2018)

Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic

af Stone, Meredith L., Chiappinelli, Katherine B., Li, Huili, Murphy, Lauren M., Travers, Meghan E., Topper, Michael J., Mathios, Dimitrios, Lim, Michael, Shih, Ie-Ming, Wang, Tian-Li, Hung, Chien-Fu, Bhargava, Vipul, Wiehagen, Karla R., Cowley, Glenn S., Bachman, Kurtis E., Strick, Reiner, Strissel, Pamela L., Baylin, Stephen B., Zahnow, Cynthia A.
Udgivet i Proc Natl Acad Sci U S A (2018)

Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

af Patel, Mira A., Kim, Jennifer E., Theodros, Debebe, Tam, Ada, Velarde, Esteban, Kochel, Christina M., Francica, Brian, Nirschl, Thomas R., Ghasemzadeh, Ali, Mathios, Dimitrios, Harris-Bookman, Sarah, Jackson, Christopher C., Jackson, Christina, Ye, Xiaobu, Tran, Phuoc T., Tyler, Betty, Coric, Vladimir, Selby, Mark, Brem, Henry, Drake, Charles G., Pardoll, Drew M., Lim, Michael
Udgivet i J Immunother Cancer (2016)

Erratum to: Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

af Patel, Mira A., Kim, Jennifer E., Theodros, Debebe, Tam, Ada, Velarde, Esteban, Kochel, Christina M., Francica, Brian, Nirschl, Thomas R., Ghasemzadeh, Ali, Mathios, Dimitrios, Harris-Bookman, Sarah, Jackson, Christopher C., Jackson, Christina, Ye, Xiaobu, Tran, Phuoc T., Tyler, Betty, Coric, Vladimir, Selby, Mark, Brem, Henry, Drake, Charles G., Pardoll, Drew M., Lim, Michael
Udgivet i J Immunother Cancer (2016)

Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas

af Kim, Jennifer E., Patel, Mira A., Mangraviti, Antonella, Kim, Eileen S., Theodros, Debebe, Velarde, Esteban, Liu, Ann, Sankey, Eric W., Tam, Ada, Xu, Haiying, Mathios, Dimitrios, Jackson, Christopher M., Harris-Bookman, Sarah, Garzon-Muvdi, Tomas, Sheu, Mary, Martin, Allison M., Tyler, Betty M., Tran, Phuoc T., Ye, Xiaobu, Olivi, Alessandro, Taube, Janis M., Burger, Peter C., Drake, Charles G., Brem, Henry, Pardoll, Drew M., Lim, Michael
Udgivet i Clin Cancer Res (2016)