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Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma

The study of survival outliers of glioblastoma can provide important clues on gliomagenesis as well as on the ways to alter clinical course of this almost uniformly lethal cancer type. However, there has been little consensus on genetic and epigenetic signatures of the long-term survival outliers of...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Acta Neuropathol Commun
Main Authors: Hwang, Taeyoung, Mathios, Dimitrios, McDonald, Kerrie L., Daris, Irene, Park, Sung-Hye, Burger, Peter C., Kim, Sojin, Dho, Yun-Sik, Carolyn, Hruban, Bettegowda, Chetan, Shin, Joo Heon, Lim, Michael, Park, Chul-Kee
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545689/
https://ncbi.nlm.nih.gov/pubmed/31159876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0744-0
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