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P04.32 Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced de-novo mutation in survival outliers of glioblastoma

BACKGROUND: The study of survival outliers of glioblastoma (GBM) can have important implications on gliomagenesis as well as in the identification of ways to alter clinical course on this almost uniformly lethal cancer type. However, current studied epigenetic and genetic signatures of the GBM outli...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Hwang, T, Mathios, D, McDonald, K, Daris, I, Park, S, Burger, P, Kim, S, Dho, Y, Hruban, C, Bettegowda, C, Shin, J, Lim, M, Park, C
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144479/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.266
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