Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma

The study of survival outliers of glioblastoma can provide important clues on gliomagenesis as well as on the ways to alter clinical course of this almost uniformly lethal cancer type. However, there has been little consensus on genetic and epigenetic signatures of the long-term survival outliers of...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Hwang, Taeyoung, Mathios, Dimitrios, McDonald, Kerrie L., Daris, Irene, Park, Sung-Hye, Burger, Peter C., Kim, Sojin, Dho, Yun-Sik, Carolyn, Hruban, Bettegowda, Chetan, Shin, Joo Heon, Lim, Michael, Park, Chul-Kee
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545689/
https://ncbi.nlm.nih.gov/pubmed/31159876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0744-0
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