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Novel Human Interleukin-15 Agonists

IL-15 is an immunostimulatory cytokine trans-presented with the IL-15 receptor α chain to the shared IL-2/IL-15Rβ and common γ chains displayed on the surface of T cells and NK cells. To further define the functionally important regions of this cytokine, activity and binding studies were conducted o...

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Detalhes bibliográficos
Main Authors: Zhu, Xiaoyun, Marcus, Warren D., Xu, Wenxin, Lee, Hyung-Il, Han, Kaiping, Egan, Jack O., Yovandich, Jason L., Rhode, Peter R., Wong, Hing C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814526/
https://ncbi.nlm.nih.gov/pubmed/19710453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901244
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