The IL-15-based superagonist ALT-803 promotes the antigen-independent conversion of memory CD8(+) T cells into innate-like effector cells with antitumor activity

por Wong, Hing C, Jeng, Emily K, Rhode, Peter R
Publicado em 2013

Metal toxicity and opportunistic binding of Pb(2+) in proteins

por Kirberger, Michael, Wong, Hing C., Jiang, Jie, Yang, Jenny J
Publicado em 2013

(1)H, (15)N, and (13)C resonance assignments for a monomeric mutant of the HIV-1 capsid protein

por Shin, Ronald, Tzou, Ywh-Min, Wong, Hing C., Krishna, N. Rama
Publicado em 2011

Enhanced efficacy of IL-15-based ALT-803 superagonist complex in combination with immune checkpoint inhibitors in hematologic and metastatic mouse tumor models

por Xu, Wenxin, Marcus, Warren D, Rhode, Peter R, Wong, Hing C
Publicado no J Immunother Cancer (2014)

Intravesical ALT-803 for BCG-unresponsive Bladder Cancer – A Case Report

por Huang, Jeffrey, Schisler, John, Wong, Hing C., Rosser, Charles J., Sterbis, Joseph
Publicado no Urol Case Rep (2017)

An IL-15 superagonist/IL-15Rα fusion complex protects and rescues NK cell-cytotoxic function from TGF-β1-mediated immunosuppression

por Fujii, Rika, Jochems, Caroline, Tritsch, Sarah R., Wong, Hing C., Schlom, Jeffrey, Hodge, James W.
Publicado no Cancer Immunol Immunother (2018)

IL15N72D superagonist/IL15Rα-Fc fusion complex (ALT-803) exhibits anti-metastatic activity in murine breast tumor model

por Kim, Peter S, Kwilas, Anna R, Jeng, Emily K, Wong, Hing C, Schlom, Jeffrey, Hodge, James W
Publicado no J Immunother Cancer (2015)

Sequestosome 1/p62 Is a Polyubiquitin Chain Binding Protein Involved in Ubiquitin Proteasome Degradation

por Seibenhener, M. Lamar, Babu, Jeganathan Ramesh, Geetha, Thangiah, Wong, Hing C., Krishna, N. Rama, Wooten, Marie W.
Publicado em 2004

Predicting Ca(2+)-binding Sites Using Refined Carbon Clusters

por Zhao, Kun, Wang, Xue, Wong, Hing C., Wohlhueter, Robert, Kirberger, Michael P., Chen, Guantao, Yang, Jenny J.
Publicado em 2012

Evaluation of a novel CD20-targeted IL-15 immunotherapeutic with potent activity against B cell lymphoma

por Liu, Bai, Kong, Lin, Marcus, Warren D, Chen, Xiaoyue, Han, Kaiping, Rhode, Peter R, Wong, Hing C
Publicado no J Immunother Cancer (2014)

CITN-06: a Phase I/expansion trial of alt-803, an IL-15 superagonist, in patients with advanced melanoma

por Margolin, Kim, Wong, Hing C, Morishima, Chihiro, Hernandez, Liza, Ernstoff, Marc, Rhode, Peter R, Waldmann, Thomas A
Publicado no J Immunother Cancer (2014)

Enhanced efficacy of ALT-803, an IL-15-based superagonist complex, in combination with immune checkpoint inhibitors in an orthotopic muscle invasive bladder tumor model in mice

por Xu, Wenxin, Kage, Karen, Marcus, Warren D, Newman, Robby, Alter, Sarah, Rhode, Peter R, Wong, Hing C
Publicado no J Immunother Cancer (2015)

An IL-15 Superagonist, ALT-803, Enhances Antibody-Dependent Cell-Mediated Cytotoxicity Elicited by the Monoclonal Antibody NEO-201 Against Human Carcinoma Cells

por Fantini, Massimo, David, Justin M., Wong, Hing C., Annunziata, Christina M., Arlen, Philip M., Tsang, Kwong Y.
Publicado no Cancer Biother Radiopharm (2019)

Tissue Factor-Specific Ultra-bright SERRS Nanostars for Raman Detection of Pulmonary Micrometastases

por Nayak, Tapas R., Andreou, Chrysafis, Oseledchyk, Anton, Marcus, Warren D., Wong, Hing C., Massagué, Joan, Kircher, Moritz F.
Publicado no Nanoscale (2017)

A phase I study evaluating the pharmacokinetics, safety and tolerability of an antibody-based tissue factor antagonist in subjects with acute lung injury or acute respiratory distr...

por Morris, Peter E, Steingrub, Jay S, Huang, Bee Y, Tang, Shamay, Liu, Patrick M, Rhode, Peter R, Wong, Hing C
Publicado em 2012

Structural basis of the recognition of the Dishevelled DEP domain in the Wnt signaling pathway

por Wong, Hing C., Mao, Junhao, Nguyen, Jason T., Srinivas, Shamala, Zhang, Weixing, Liu, Bo, Li, Lin, Wu, Dianqing, Zheng, Jie
Publicado no Nat Struct Biol (2000)

ImmunoPET of Tissue Factor in Pancreatic Cancer

por Hong, Hao, Zhang, Yin, Nayak, Tapas R., Engle, Jonathan W., Wong, Hing C., Liu, Bai, Barnhart, Todd E., Cai, Weibo
Publicado em 2012

IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-...

por Kim, Peter S., Kwilas, Anna R., Xu, Wenxin, Alter, Sarah, Jeng, Emily K., Wong, Hing C., Schlom, Jeffrey, Hodge, James W.
Publicado no Oncotarget (2016)

ImmunoPET imaging of tissue factor expression in pancreatic cancer with (89)Zr-Df-ALT-836

por Hernandez, Reinier, England, Christopher G., Yang, Yunan, Valdovinos, Hector F., Liu, Bai, Wong, Hing C., Barnhart, Todd E., Cai, Weibo
Publicado no J Control Release (2017)

The IL-15 superagonist ALT-803 enhances anti-CD20 antibody-directed NK cell ADCC and in vivo clearance of B cell lymphomas

por Rosario, Maximillian, Liu, Bai, Kong, Lin, Schneider, Stephanie E, Jeng, Emily K, Rhode, Peter R, Wong, Hing C, Fehniger, Todd A
Publicado no J Immunother Cancer (2014)