Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response

by Reshkin, Stephan J., Cardone, Rosa Angela
Published in Cancers (Basel) (2020)

Synergy Between Low Dose Metronomic Chemotherapy and the pH-Centered Approach Against Cancer

by Koltai, Tomas, Cardone, Rosa A., Reshkin, Stephan J.
Published in Int J Mol Sci (2019)

Metabolic Shifts as the Hallmark of Most Common Diseases: The Quest for the Underlying Unity

by Schwartz, Laurent, Henry, Marc, Alfarouk, Khalid O., Reshkin, Stephan J., Radman, Miroslav
Published in Int J Mol Sci (2021)

The Na(+)–H(+ )exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells

by Paradiso, Angelo, Cardone, Rosa Angela, Bellizzi, Antonia, Bagorda, Anna, Guerra, Lorenzo, Tommasino, Massimo, Casavola, Valeria, Reshkin, Stephan J
Published 2004

CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity

by Monterisi, Stefania, Favia, Maria, Guerra, Lorenzo, Cardone, Rosa A., Marzulli, Domenico, Reshkin, Stephan J., Casavola, Valeria, Zaccolo, Manuela
Published 2012

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs – an integral molecular/biochemical/metabolic/clinical approach after one hundred ye...

by Harguindey, Salvador, Arranz, Jose Luis, Polo Orozco, Julian David, Rauch, Cyril, Fais, Stefano, Cardone, Rosa Angela, Reshkin, Stephan J
Published 2013

Protein Kinase A Gating of a Pseudopodial-located RhoA/ROCK/p38/NHE1 Signal Module Regulates Invasion in Breast Cancer Cell Lines

by Cardone, Rosa A., Bagorda, Anna, Bellizzi, Antonia, Busco, Giovanni, Guerra, Lorenzo, Paradiso, Angelo, Casavola, Valeria, Zaccolo, Manuela, Reshkin, Stephan J.
Published 2005

The NHERF1 PDZ2 Domain Regulates PKA–RhoA–p38-mediated NHE1 Activation and Invasion in Breast Tumor Cells

by Cardone, Rosa A., Bellizzi, Antonia, Busco, Giovanni, Weinman, Edward J., Dell'Aquila, Maria E., Casavola, Valeria, Azzariti, Amalia, Mangia, Anita, Paradiso, Angelo, Reshkin, Stephan J.
Published 2007

Proton dynamics in cancer

by Huber, Veronica, De Milito, Angelo, Harguindey, Salvador, Reshkin, Stephan J, Wahl, Miriam L, Rauch, Cyril, Chiesi, Antonio, Pouysségur, Jacques, Gatenby, Robert A, Rivoltini, Licia, Fais, Stefano
Published 2010

E6 and E7 from Human Papillomavirus Type 16 Cooperate To Target the PDZ Protein Na/H Exchange Regulatory Factor 1

by Accardi, Rosita, Rubino, Rosa, Scalise, Mariafrancesca, Gheit, Tarik, Shahzad, Naveed, Thomas, Miranda, Banks, Lawrence, Indiveri, Cesare, Sylla, Bakary S., Cardone, Rosa A., Reshkin, Stephan J., Tommasino, Massimo
Published 2011

ß1 Integrin Binding Phosphorylates Ezrin at T567 to Activate a Lipid Raft Signalsome Driving Invadopodia Activity and Invasion

by Antelmi, Ester, Cardone, Rosa A., Greco, Maria R., Rubino, Rosa, Di Sole, Francesca, Martino, Nicola A., Casavola, Valeria, Carcangiu, MariaLuisa, Moro, Loredana, Reshkin, Stephan J.
Published 2013

HPV16 E7-Dependent Transformation Activates NHE1 through a PKA-RhoA-Iinduced Inhibition of p38alpha

by Cardone, Rosa A., Busco, Giovanni, Greco, Maria R., Bellizzi, Antonia, Accardi, Rosita, Cafarelli, Antonella, Monterisi, Stefania, Carratù, Pierluigi, Casavola, Valeria, Paradiso, Angelo, Tommasino, Massimo, Reshkin, Stephan J.
Published 2008

pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology

by Pethő, Zoltán, Najder, Karolina, Carvalho, Tiago, McMorrow, Roisin, Todesca, Luca Matteo, Rugi, Micol, Bulk, Etmar, Chan, Alan, Löwik, Clemens W. G. M., Reshkin, Stephan J., Schwab, Albrecht
Published in Cancers (Basel) (2020)

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

by Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Adil, H. H Bashir, Elhassan, Gamal O., Ibrahim, Muntaser E., David Polo Orozco, Julian, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador
Published in Oncoscience (2014)

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

by Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Bashir, Adil H. H., Elhassan, Gamal O., Ibrahim, Muntaser E., Orozco, Julian David Polo, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador
Published in Oncoscience (2014)

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

by Alfarouk, Khalid O, Stock, Christian-Martin, Taylor, Sophie, Walsh, Megan, Muddathir, Abdel Khalig, Verduzco, Daniel, Bashir, Adil H H, Mohammed, Osama Y, Elhassan, Gamal O, Harguindey, Salvador, Reshkin, Stephan J, Ibrahim, Muntaser E, Rauch, Cyril
Published in Cancer Cell Int (2015)

The Interplay of Dysregulated pH and Electrolyte Imbalance in Cancer

by Alfarouk, Khalid O., Ahmed, Samrein B. M., Ahmed, Ahmed, Elliott, Robert L., Ibrahim, Muntaser E., Ali, Heyam S., Wales, Christian C., Nourwali, Ibrahim, Aljarbou, Ahmed N., Bashir, Adil H. H., Alhoufie, Sari T. S., Alqahtani, Saad Saeed, Cardone, Rosa A., Fais, Stefano, Harguindey, Salvador, Reshkin, Stephan J.
Published in Cancers (Basel) (2020)

Pathogenesis and Management of COVID-19

by Alfarouk, Khalid O., AlHoufie, Sari T. S., Ahmed, Samrein B. M., Shabana, Mona, Ahmed, Ahmed, Alqahtani, Saad S., Alqahtani, Ali S., Alqahtani, Ali M., Ramadan, AbdelRahman M., Ahmed, Mohamed E., Ali, Heyam S., Bashir, Adil, Devesa, Jesus, Cardone, Rosa A., Ibrahim, Muntaser E., Schwartz, Laurent, Reshkin, Stephan J.
Published in J Xenobiot (2021)

The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management

by Alfarouk, Khalid O., Bashir, Adil H. H., Aljarbou, Ahmed N., Ramadan, AbdelRahman M., Muddathir, Abdel Khalig, AlHoufie, Sari T. S., Hifny, Abdelhamid, Elhassan, Gamal O., Ibrahim, Muntaser E., Alqahtani, Saad S., AlSharari, Shakir D., Supuran, Claudiu T., Rauch, Cyril, Cardone, Rosa Angela, Reshkin, Stephan J., Fais, Stefano, Harguindey, Salvador
Published in Front Oncol (2019)

The Pentose Phosphate Pathway Dynamics in Cancer and Its Dependency on Intracellular pH

by Alfarouk, Khalid O., Ahmed, Samrein B. M., Elliott, Robert L., Benoit, Amanda, Alqahtani, Saad S., Ibrahim, Muntaser E., Bashir, Adil H. H., Alhoufie, Sari T. S., Elhassan, Gamal O., Wales, Christian C., Schwartz, Laurent H., Ali, Heyam S., Ahmed, Ahmed, Forde, Patrick F., Devesa, Jesus, Cardone, Rosa A., Fais, Stefano, Harguindey, Salvador, Reshkin, Stephan J.
Published in Metabolites (2020)