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Protein Kinase A Gating of a Pseudopodial-located RhoA/ROCK/p38/NHE1 Signal Module Regulates Invasion in Breast Cancer Cell Lines

Metastasis results from a sequence of selective events often involving interactions with elements of the tumor-specific physiological microenvironment. The low-serum component of this microenvironment confers increased motility and invasion in breast cancer cells by activating the Na(+)/H(+) exchang...

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Autors principals: Cardone, Rosa A., Bagorda, Anna, Bellizzi, Antonia, Busco, Giovanni, Guerra, Lorenzo, Paradiso, Angelo, Casavola, Valeria, Zaccolo, Manuela, Reshkin, Stephan J.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165397/
https://ncbi.nlm.nih.gov/pubmed/15843433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-10-0945
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