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A TRANSCRIPTIONAL CROSS–TALK BETWEEN RhoA AND c–Myc INHIBITS THE RhoA/Rock–DEPENDENT CYTOSKELETON

The GTPase RhoA participates in a number of cellular processes, including cytoskeletal organization, mitogenesis and tumorigenesis. We have previously shown that the transforming activity of an oncogenic version of RhoA (Q63L mutant) was highly dependent on the transcriptional factor c–Myc. In contr...

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書誌詳細
主要な著者: Sauzeau, Vincent, Berenjeno, Inmaculada M., Citterio, Carmen, Bustelo, Xosé R.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896432/
https://ncbi.nlm.nih.gov/pubmed/20453885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.134
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