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A TRANSCRIPTIONAL CROSS–TALK BETWEEN RhoA AND c–Myc INHIBITS THE RhoA/Rock–DEPENDENT CYTOSKELETON

The GTPase RhoA participates in a number of cellular processes, including cytoskeletal organization, mitogenesis and tumorigenesis. We have previously shown that the transforming activity of an oncogenic version of RhoA (Q63L mutant) was highly dependent on the transcriptional factor c–Myc. In contr...

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Autori principali: Sauzeau, Vincent, Berenjeno, Inmaculada M., Citterio, Carmen, Bustelo, Xosé R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896432/
https://ncbi.nlm.nih.gov/pubmed/20453885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.134
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