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A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton

The GTPase RhoA and the transcriptional factor c-Myc are closely intertwined in cancer cells. Although this cross-talk results in potent synergistic effects that favor the transformed phenotype of cancer cells, recent results from our laboratory indicate that c-Myc also participates in a negative fe...

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Autore principale: Bustelo, Xosé R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109477/
https://ncbi.nlm.nih.gov/pubmed/21686122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.1.1.12986
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