RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism

The ubiquitously expressed small GTPase RhoA is essential for embryonic development and mutated in different cancers. Functionally, it is well described as a regulator of the actin cytoskeleton, but its role in gene regulation is less understood. Using primary mouse keratinocytes with a deletion of...

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Publicat a:Small GTPases
Autors principals: García-Mariscal, Alberto, Peyrollier, Karine, Basse, Astrid, Pedersen, Esben, Rühl, Ralph, van Hengel, Jolanda, Brakebusch, Cord
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997168/
https://ncbi.nlm.nih.gov/pubmed/27754752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1248272
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