RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism

The ubiquitously expressed small GTPase RhoA is essential for embryonic development and mutated in different cancers. Functionally, it is well described as a regulator of the actin cytoskeleton, but its role in gene regulation is less understood. Using primary mouse keratinocytes with a deletion of...

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Vydáno v:Small GTPases
Hlavní autoři: García-Mariscal, Alberto, Peyrollier, Karine, Basse, Astrid, Pedersen, Esben, Rühl, Ralph, van Hengel, Jolanda, Brakebusch, Cord
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997168/
https://ncbi.nlm.nih.gov/pubmed/27754752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1248272
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