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RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism

The ubiquitously expressed small GTPase RhoA is essential for embryonic development and mutated in different cancers. Functionally, it is well described as a regulator of the actin cytoskeleton, but its role in gene regulation is less understood. Using primary mouse keratinocytes with a deletion of...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: García-Mariscal, Alberto, Peyrollier, Karine, Basse, Astrid, Pedersen, Esben, Rühl, Ralph, van Hengel, Jolanda, Brakebusch, Cord
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997168/
https://ncbi.nlm.nih.gov/pubmed/27754752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1248272
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