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RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes
RhoA is a small guanosine-5’-triphosphatase (GTPase) suggested to be essential for cytokinesis, stress fiber formation, and epithelial cell–cell contacts. In skin, loss of RhoA was suggested to underlie pemphigus skin blistering. To analyze RhoA function in vivo, we generated mice with a keratinocyt...
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| Huvudupphovsmän: | , , , , , , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The American Society for Cell Biology
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046057/ https://ncbi.nlm.nih.gov/pubmed/21209320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-10-0859 |
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