RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

RhoA is a small guanosine-5’-triphosphatase (GTPase) suggested to be essential for cytokinesis, stress fiber formation, and epithelial cell–cell contacts. In skin, loss of RhoA was suggested to underlie pemphigus skin blistering. To analyze RhoA function in vivo, we generated mice with a keratinocyt...

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Main Authors: Jackson, Ben, Peyrollier, Karine, Pedersen, Esben, Basse, Astrid, Karlsson, Richard, Wang, Zhipeng, Lefever, Tine, Ochsenbein, Alexandra M., Schmidt, Gudula, Aktories, Klaus, Stanley, Alanna, Quondamatteo, Fabio, Ladwein, Markus, Rottner, Klemens, van Hengel, Jolanda, Brakebusch, Cord
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046057/
https://ncbi.nlm.nih.gov/pubmed/21209320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-10-0859
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