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Cdc42 Is Not Essential for Filopodium Formation, Directed Migration, Cell Polarization, and Mitosis in Fibroblastoid Cells

Cdc42 is a small GTPase involved in the regulation of the cytoskeleton and cell polarity. To test whether Cdc42 has an essential role in the formation of filopodia or directed cell migration, we generated Cdc42-deficient fibroblastoid cells by conditional gene inactivation. We report here that loss...

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Bibliografiset tiedot
Päätekijät: Czuchra, Aleksandra, Wu, Xunwei, Meyer, Hannelore, van Hengel, Jolanda, Schroeder, Timm, Geffers, Robert, Rottner, Klemens, Brakebusch, Cord
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2005
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237057/
https://ncbi.nlm.nih.gov/pubmed/16014609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-01-0061
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