Cdc42 controls progenitor cell differentiation and β-catenin turnover in skin

Differentiation of skin stem cells into hair follicles (HFs) requires the inhibition of β-catenin degradation, which is controlled by a complex containing axin and the protein kinase GSK3β. Using conditional gene targeting in mice, we show now that the small GTPase Cdc42 is crucial for differentiati...

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Bibliographic Details
Main Authors: Wu, Xunwei, Quondamatteo, Fabio, Lefever, Tine, Czuchra, Aleksandra, Meyer, Hannelore, Chrostek, Anna, Paus, Ralf, Langbein, Lutz, Brakebusch, Cord
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410804/
https://ncbi.nlm.nih.gov/pubmed/16510873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.361406
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