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Cdc42 controls progenitor cell differentiation and β-catenin turnover in skin
Differentiation of skin stem cells into hair follicles (HFs) requires the inhibition of β-catenin degradation, which is controlled by a complex containing axin and the protein kinase GSK3β. Using conditional gene targeting in mice, we show now that the small GTPase Cdc42 is crucial for differentiati...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1410804/ https://ncbi.nlm.nih.gov/pubmed/16510873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.361406 |
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